000107457 001__ 107457
000107457 005__ 20230519145410.0
000107457 0247_ $$2doi$$a10.3390/ijerph18147238
000107457 0248_ $$2sideral$$a124895
000107457 037__ $$aART-2021-124895
000107457 041__ $$aeng
000107457 100__ $$0(orcid)0000-0002-1113-9169$$aPerez-Lasierra, Jose Luis$$uUniversidad de Zaragoza
000107457 245__ $$aCan Physical Activity Reduce the Risk of Cognitive Decline in Apolipoprotein e4 Carriers? A Systematic Review
000107457 260__ $$c2021
000107457 5060_ $$aAccess copy available to the general public$$fUnrestricted
000107457 5203_ $$aPhysical activity (PA) reduces the risk of cognitive decline (CD) in the general population. However, little is known about whether the presence of the apolipoprotein E epsilon 4 allele (APOE e4) could modify this beneficial effect. The aim of this systematic review was to analyze and synthetize the scientific evidence related to PA levels and CD risk in cognitively healthy APOE e4 carriers. Four electronic databases were analyzed. Only original articles with longitudinal study design were selected to analyze the relationship between PA and CD in APOE e4 carriers. Five studies were included in the systematic review. All studies except one stated that PA is a protective factor against CD in APOE e4 carriers. Moreover, partial support was found for the hypothesis that a greater amount and intensity of PA are more beneficial in CD prevention. The results support the idea that PA is a protective factor against CD in APOE e4 carriers. Nevertheless, it would be necessary to carry out further studies that would allow these findings to be contrasted.
000107457 536__ $$9info:eu-repo/grantAgreement/ES/MECD/FPU16-02539$$9info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI19-00948
000107457 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000107457 590__ $$a4.614$$b2021
000107457 592__ $$a0.814$$b2021
000107457 594__ $$a4.5$$b2021
000107457 591__ $$aPUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH$$b45 / 183 = 0.246$$c2021$$dQ1$$eT1
000107457 593__ $$aPollution$$c2021$$dQ1
000107457 591__ $$aPUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH$$b71 / 210 = 0.338$$c2021$$dQ2$$eT2
000107457 593__ $$aHealth, Toxicology and Mutagenesis$$c2021$$dQ1
000107457 591__ $$aENVIRONMENTAL SCIENCES$$b100 / 279 = 0.358$$c2021$$dQ2$$eT2
000107457 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000107457 700__ $$0(orcid)0000-0002-7215-6931$$aCasajús, Jose Antonio$$uUniversidad de Zaragoza
000107457 700__ $$0(orcid)0000-0002-9887-2629$$aCasasnovas, José Antonio$$uUniversidad de Zaragoza
000107457 700__ $$0(orcid)0000-0002-8982-3737$$aArbones-Mainar, Jose Miguel
000107457 700__ $$0(orcid)0000-0002-9098-655X$$aLobo, Antonio$$uUniversidad de Zaragoza
000107457 700__ $$0(orcid)0000-0002-1252-2397$$aLobo, Elena$$uUniversidad de Zaragoza
000107457 700__ $$0(orcid)0000-0003-0604-5042$$aMoreno-Franco, Belén$$uUniversidad de Zaragoza
000107457 700__ $$0(orcid)0000-0002-1132-5906$$aGonzalez-Agüero, Alejandro$$uUniversidad de Zaragoza
000107457 7102_ $$11006$$2245$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Educación Física y Depor.
000107457 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000107457 7102_ $$11007$$2745$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Psiquiatría
000107457 7102_ $$11011$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Medic.Prevent.Salud Públ.
000107457 773__ $$g18, 14 (2021), 7238 [15 p.]$$pInt. j. environ. res. public health$$tInternational journal of environmental research and public health$$x1661-7827
000107457 8564_ $$s597927$$uhttps://zaguan.unizar.es/record/107457/files/texto_completo.pdf$$yVersión publicada
000107457 8564_ $$s2867563$$uhttps://zaguan.unizar.es/record/107457/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000107457 909CO $$ooai:zaguan.unizar.es:107457$$particulos$$pdriver
000107457 951__ $$a2023-05-18-13:54:02
000107457 980__ $$aARTICLE