000108299 001__ 108299
000108299 005__ 20220908120458.0
000108299 0247_ $$2doi$$a10.1016/j.regg.2020.10.005
000108299 0248_ $$2sideral$$a121601
000108299 037__ $$aART-2021-121601
000108299 041__ $$aspa
000108299 100__ $$aMoreno Borraz, L.A.
000108299 245__ $$aPrevalencia de infección por coronavirus SARS-CoV-2 en pacientes y profesionales de un hospital de media y larga estancia en España
000108299 260__ $$c2021
000108299 5060_ $$aAccess copy available to the general public$$fUnrestricted
000108299 5203_ $$aBackground and goals: The aim of the study is to know the prevalence of SARS-CoV-2 infection in patients and professional staff of a medium or long-stay hospital during the peak period of the pandemic in Spain, spring 2020.
Material and methods: At the end of February 2020, we developed at the hospital a strategy to diagnose the SARS-CoV-2 infection consisting of complementing the realization of PCR tests at real time with a quick technique of lateral flow immunochromatography to detect IgG and IgM antibodies against the virus. We also developed a protocol to realize those diagnostic tests and considered an infection (current or past) a positive result in any of the above tests. We included 524 participants in the study (230 patients and 294 hospital staff), and divided them into hospital patients and Hemodialysis outpatients. Furthermore, we divided the hospital staff into healthcare and non-healthcare staff. The documented period was from March, 20th to April, 21st, 2020.
Results: 26 out of 230 patients tested positive in any of the diagnostic techniques (PCR, antibodies IgG, IgM) with a 11.30% prevalence. According to patients groups, we got a 14.38% prevalence in hospital patients vs. 5.95% in outpatients, with a significantly higher risk in admitted patients after adjustment for age and gender (OR=3, 309, 95%CI: 1, 154-9, 495). 24 out of 294 hospital staff tested positive in any of the diagnostic techniques, with a 8.16% prevalence. According to the groups, we got a 8.91% prevalence in healthcare staff vs. 4.26% in non-healthcare staff. Thus, we do not see any statistically significant differences between hospital staff and patients as far as prevalence is concerned (P=0, 391), (OR=2, 200, 95%CI: 0, 500-9, 689).
Conclusions: The result of the study was a quite low prevalence rate of SARS-CoV-2 infection, in both patients and hospital staff, being the hospital patients’ prevalence rate higher than the outpatients’, and the healthcare staff higher than the non-healthcare''s. Combining PCR tests (gold standard) with antibodies tests proved useful as a diagnostic strategy.
000108299 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000108299 592__ $$a0.243$$b2021
000108299 593__ $$aGeriatrics and Gerontology$$c2021$$dQ4
000108299 593__ $$aAging$$c2021$$dQ4
000108299 594__ $$a1.3$$b2021
000108299 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000108299 700__ $$0(orcid)0000-0001-6647-2981$$aGiménez López, M.$$uUniversidad de Zaragoza
000108299 700__ $$aCarrera Lasfuentes, P.
000108299 700__ $$0(orcid)0000-0001-9339-8115$$aGonzález Pérez, E.
000108299 700__ $$aOrtíz Domingo, C.
000108299 700__ $$aBonafonte Marteles, J.L.
000108299 700__ $$aVicente Gaspar, C.
000108299 700__ $$aAmorós de la Nieta, F.
000108299 700__ $$aSastre Heres, A.
000108299 700__ $$aGarcía Forcada, Á.L.
000108299 700__ $$aSerrano Herrero, M.P.
000108299 700__ $$aFernández Doblado, S.
000108299 700__ $$aEspinosa Val, M.C.$$uUniversidad de Zaragoza
000108299 700__ $$aFernández Adarve, M.M.
000108299 700__ $$aNarvión Carriquiri, A.
000108299 700__ $$aArto Maza, F.
000108299 700__ $$aBarea Gil, M.
000108299 700__ $$aAznar Vázquez, I.
000108299 700__ $$aSisas Rubio, R.
000108299 700__ $$aGonzález Tejedor, R.
000108299 700__ $$aFlorentín Ostáriz, E.$$uUniversidad de Zaragoza
000108299 700__ $$aLópez Santed, C.
000108299 700__ $$aMolina Morales, A.R.
000108299 700__ $$aParrilla Binué, S.
000108299 700__ $$aPérez Sans, J.
000108299 700__ $$aGarcía Mena, M.
000108299 700__ $$aMoragrega Cardona, B.
000108299 700__ $$aLuzón Alonso, M.
000108299 700__ $$aDíaz Mora, F.
000108299 700__ $$aGil Acebes, J.C.
000108299 700__ $$aRubio Morilla, Y.
000108299 700__ $$aLou Lou, R.
000108299 700__ $$aZabala Lahoz, R.B.
000108299 700__ $$0(orcid)0000-0003-0292-3119$$aCoarasa Lirón de Robles, A.$$uUniversidad de Zaragoza
000108299 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000108299 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000108299 7102_ $$11013$$2090$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Cirugía
000108299 773__ $$g56, 2 (2021), 75-80$$pRev. esp. geriatr. gerontol.$$tRevista Espanola de Geriatria y Gerontologia$$x0211-139X
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000108299 951__ $$a2022-09-08-11:54:12
000108299 980__ $$aARTICLE