000108315 001__ 108315 000108315 005__ 20230519145352.0 000108315 0247_ $$2doi$$a10.1016/j.engfracmech.2020.107067 000108315 0248_ $$2sideral$$a121158 000108315 037__ $$aART-2021-121158 000108315 041__ $$aeng 000108315 100__ $$aSilberschmidt, V.V. 000108315 245__ $$aDamage and fracture of biological and biomedical materials 000108315 260__ $$c2021 000108315 5060_ $$aAccess copy available to the general public$$fUnrestricted 000108315 5203_ $$aIn the last decade, the topic of damage and fracture of biological and biomedical materials not only became one of the central research areas in the healthcare engineering, but also drew attention of specialists in mechanics of materials and fracture. One of the motivations behind these developments is a continuing increase in the use of medical devices made of various materials that are exposed to challenging loading and environmental conditions. Many of them should have significant levels of durability to avoid recurring surgical interventions (typical examples being implants for hip and knee replacements or dental implants). A lack of understanding of their responses to specific conditions and interaction with biological environment can result in malfunctioning and failures or traumas to surrounding tissues. The typical application problems are additionally complicated by insufficient knowledge of mechanical behaviour of biomaterials at various length and time scales and under different loading conditions including their fracture and fatigue. These types of application presuppose the understanding of properties and performance of two classes of materials – natural (biomaterials) and engineering (biomedical materials), as well as their interaction at interfaces between, on the one hand, life tissues (or organs) and, on the other hand, implants and prostheses. Among engineering materials, used in such applications, are familiar metals and alloys, ceramics, polymers and composites. Their properties and performance seem to be well studied; still, biomedical applications are characterised by rather specific usability envelopes as well as, in most cases, additional constraints such as non-toxicity (biocompatibility) and/or resistance to harsh physiological environments. In some cases, a requirement, opposite to structural integrity, is needed, e.g. controlled degradation for scaffolds and stents... 000108315 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/ 000108315 590__ $$a4.898$$b2021 000108315 591__ $$aMECHANICS$$b19 / 138 = 0.138$$c2021$$dQ1$$eT1 000108315 594__ $$a7.8$$b2021 000108315 592__ $$a1.252$$b2021 000108315 593__ $$aMechanical Engineering$$c2021$$dQ1 000108315 593__ $$aMaterials Science (miscellaneous)$$c2021$$dQ1 000108315 655_4 $$ainfo:eu-repo/semantics/other$$vinfo:eu-repo/semantics/acceptedVersion 000108315 700__ $$0(orcid)0000-0002-9864-7683$$aGarcia Aznar, J.M.$$uUniversidad de Zaragoza 000108315 7102_ $$15004$$2605$$aUniversidad de Zaragoza$$bDpto. Ingeniería Mecánica$$cÁrea Mec.Med.Cont. y Teor.Est. 000108315 773__ $$g241, 107067 (2021), [2 pp]$$pEng. fract. mech.$$tENGINEERING FRACTURE MECHANICS$$x0013-7944 000108315 8564_ $$s257919$$uhttps://zaguan.unizar.es/record/108315/files/texto_completo.pdf$$yPostprint 000108315 8564_ $$s2644939$$uhttps://zaguan.unizar.es/record/108315/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint 000108315 909CO $$ooai:zaguan.unizar.es:108315$$particulos$$pdriver 000108315 951__ $$a2023-05-18-13:27:17 000108315 980__ $$aARTICLE