000108329 001__ 108329
000108329 005__ 20211115135505.0
000108329 0247_ $$2doi$$a10.1039/d0cc06349e
000108329 0248_ $$2sideral$$a122421
000108329 037__ $$aART-2020-122421
000108329 041__ $$aeng
000108329 100__ $$0(orcid)0000-0001-6815-6720$$aMacías-León, J.$$uUniversidad de Zaragoza
000108329 245__ $$aStructural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody
000108329 260__ $$c2020
000108329 5060_ $$aAccess copy available to the general public$$fUnrestricted
000108329 5203_ $$aThe molecular basis of antibody 5E5, which recognizes the entire GalNAc unit as a primary epitope is disclosed. The antibody''s contacts with the peptide are mostly limited to two residues, allowing it to show some degree of promiscuity. These findings open the door to the chemical design of peptide-mimetics for developing efficient anti-cancer vaccines and diagnostic tools.
000108329 536__ $$9info:eu-repo/grantAgreement/ES/AEI/BFU2016-75633-P$$9info:eu-repo/grantAgreement/ES/AEI/CTQ2013-44367-C2-2-P$$9info:eu-repo/grantAgreement/ES/AEI/PID2019-105451GB-I00$$9info:eu-repo/grantAgreement/ES/AEI/PID2019-107476GB-I00$$9info:eu-repo/grantAgreement/ES/AEI/RTI-2018-099592-B-C21
000108329 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000108329 590__ $$a6.222$$b2020
000108329 591__ $$aCHEMISTRY, MULTIDISCIPLINARY$$b44 / 178 = 0.247$$c2020$$dQ1$$eT1
000108329 592__ $$a1.837$$b2020
000108329 593__ $$aCatalysis$$c2020$$dQ1
000108329 593__ $$aCeramics and Composites$$c2020$$dQ1
000108329 593__ $$aChemistry (miscellaneous)$$c2020$$dQ1
000108329 593__ $$aSurfaces, Coatings and Films$$c2020$$dQ1
000108329 593__ $$aMaterials Chemistry$$c2020$$dQ1
000108329 593__ $$aMetals and Alloys$$c2020$$dQ1
000108329 593__ $$aElectronic, Optical and Magnetic Materials$$c2020$$dQ1
000108329 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000108329 700__ $$aBermejo, I.A.
000108329 700__ $$aAsín, A.
000108329 700__ $$0(orcid)0000-0003-3791-2997$$aGarcía-García, A.$$uUniversidad de Zaragoza
000108329 700__ $$aCompañón, I.
000108329 700__ $$aJiménez-Moreno, E.
000108329 700__ $$aCoelho, H.
000108329 700__ $$aMangini, V.
000108329 700__ $$aAlbuquerque, I.S.
000108329 700__ $$aMarcelo, F.
000108329 700__ $$aAsensio, J.L.
000108329 700__ $$aBernardes, G.J.L.
000108329 700__ $$aJoshi, H.J.
000108329 700__ $$aFiammengo, R.
000108329 700__ $$aBlixt, O.
000108329 700__ $$0(orcid)0000-0002-3122-9401$$aHurtado-Guerrero, R.$$uUniversidad de Zaragoza
000108329 700__ $$aCorzana, F.
000108329 7102_ $$11002$$2060$$aUniversidad de Zaragoza$$bDpto. Bioq.Biolog.Mol. Celular$$cÁrea Bioquímica y Biolog.Mole.
000108329 773__ $$g56, 96 (2020), 15137-15140$$pChem. commun.$$tCHEMICAL COMMUNICATIONS$$x1359-7345
000108329 8564_ $$s1442738$$uhttps://zaguan.unizar.es/record/108329/files/texto_completo.pdf$$yPostprint
000108329 8564_ $$s3065220$$uhttps://zaguan.unizar.es/record/108329/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000108329 909CO $$ooai:zaguan.unizar.es:108329$$particulos$$pdriver
000108329 951__ $$a2021-11-15-08:57:01
000108329 980__ $$aARTICLE