000108398 001__ 108398
000108398 005__ 20211115162713.0
000108398 0247_ $$2doi$$a10.1016/j.jpeds.2019.08.020
000108398 0248_ $$2sideral$$a123423
000108398 037__ $$aART-2019-123423
000108398 041__ $$aeng
000108398 100__ $$aLui, K.
000108398 245__ $$aTrends in Outcomes for Neonates Born Very Preterm and Very Low Birth Weight in 11 High-Income Countries
000108398 260__ $$c2019
000108398 5060_ $$aAccess copy available to the general public$$fUnrestricted
000108398 5203_ $$aObjective
To evaluate outcome trends of neonates born very preterm in 11 high-income countries participating in the International Network for Evaluating Outcomes of neonates. Study design In a retrospective cohort study, we included 154 233 neonates admitted to 529 neonatal units between January 1, 2007, and December 31, 2015, at 24(0/7) to 31(6/7) weeks of gestational age and birth weight <1500 g. Composite outcomes were in-hospital mortality or any of severe neurologic injury, treated retinopathy of prematurity, and bronchopulmonary dysplasia (BPD); and same composite outcome excluding BPD. Secondary outcomes were mortality and individual morbidities. For each country, annual outcome trends and adjusted relative risks comparing epoch 2 (2012-2015) to epoch 1 (2007-2011) were analyzed.
Results
For composite outcome including BPD, the trend decreased in Canada and Israel but increased in Australia and New Zealand, Japan, Spain, Sweden, and the United Kingdom. For composite outcome excluding BPD, the trend decreased in all countries except Spain, Sweden, Tuscany, and the United Kingdom. The risk of composite outcome was lower in epoch 2 than epoch 1 in Canada (adjusted relative risks 0.78; 95% CI 0.74-0.82) only. The risk of composite outcome excluding BPD was significantly lower in epoch 2 compared with epoch 1 in Australia and New Zealand, Canada, Finland, Japan, and Switzerland. Mortality rates reduced in most countries in epoch 2. BPD rates increased significantly in all countries except Canada, Israel, Finland, and Tuscany.
Conclusions
In most countries, mortality decreased whereas BPD increased for neonates born very preterm.
000108398 536__ $$9info:eu-repo/grantAgreement/ES/ISCIII/FIS17-0131$$9info:eu-repo/grantAgreement/ES/RETICS-ISCIII-ERDF/RD16-0022
000108398 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000108398 590__ $$a3.7$$b2019
000108398 591__ $$aPEDIATRICS$$b10 / 128 = 0.078$$c2019$$dQ1$$eT1
000108398 592__ $$a1.145$$b2019
000108398 593__ $$aPediatrics, Perinatology and Child Health$$c2019$$dQ1
000108398 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000108398 700__ $$aLee, S.K.
000108398 700__ $$aKusuda, S.
000108398 700__ $$aAdams, M.
000108398 700__ $$aVento, M.
000108398 700__ $$aReichman, B.
000108398 700__ $$aDarlow, B.A.
000108398 700__ $$aLehtonen, L.
000108398 700__ $$aModi, N.
000108398 700__ $$aNorman, M.
000108398 700__ $$aHakansson, S.
000108398 700__ $$aBassler, D.
000108398 700__ $$aRusconi, F.
000108398 700__ $$aLodha, A.
000108398 700__ $$aYang, J.M.
000108398 700__ $$aShah, P.S.
000108398 700__ $$aMarshall, P.
000108398 700__ $$aSchmidt, P.
000108398 700__ $$aDhawan, A.
000108398 700__ $$aCraven, P.
000108398 700__ $$ade Waal, K.
000108398 700__ $$aSimmer, K.
000108398 700__ $$aGill, A.
000108398 700__ $$aPillow, J.
000108398 700__ $$aStack, J.
000108398 700__ $$aBirch, P.
000108398 700__ $$aCooke, L.
000108398 700__ $$aCasalaz, D.
000108398 700__ $$aHolberton, J.
000108398 700__ $$aStewart, A.
000108398 700__ $$aDowne, L.
000108398 700__ $$aStewart, M.
000108398 700__ $$aBajuk, B.
000108398 700__ $$aBerry, A.
000108398 700__ $$aHunt, R.
000108398 700__ $$aKilburn, C.
000108398 700__ $$aDe Paoli, T.
000108398 700__ $$aBolisetty, S.
000108398 700__ $$aParadisis, M.
000108398 700__ $$aRieger, I.
000108398 700__ $$aKoorts, P.
000108398 700__ $$aKuschel, C.
000108398 700__ $$aDoyle, L.
000108398 700__ $$aNuma, A.
000108398 700__ $$aCarlisle, H.
000108398 700__ $$aBadawi, N.
000108398 700__ $$aLoughran-Fowlds, A.
000108398 700__ $$aKoh, G.
000108398 700__ $$aDavis, J.
000108398 700__ $$aLuig, M.
000108398 700__ $$aAndersen, C.
000108398 700__ $$aChambers, G.
000108398 700__ $$aAustin, N.
000108398 700__ $$aLynn, A.
000108398 700__ $$aDarlow, B.
000108398 700__ $$aEdmonds, L.
000108398 700__ $$aMildenhall, L.
000108398 700__ $$aBuksh, M.
000108398 700__ $$aBattin, M.
000108398 700__ $$avan den Boom, J.
000108398 700__ $$aBourchier, D.
000108398 700__ $$aRichardson, V.
000108398 700__ $$aDineen, F.
000108398 700__ $$aRajadurai, V.S.
000108398 700__ $$aLam, S.
000108398 700__ $$aFung, G.
000108398 700__ $$aHarrison, A.
000108398 700__ $$aSynnes, A.
000108398 700__ $$aCieslak, Z.
000108398 700__ $$aSherlock, R.
000108398 700__ $$aYee, W.
000108398 700__ $$aAziz, K.
000108398 700__ $$aFajardo, C.
000108398 700__ $$aKalapesi, Z.
000108398 700__ $$aSankaran, K.
000108398 700__ $$aDaspal, S.
000108398 700__ $$aSeshia, M.
000108398 700__ $$aAlvaro, R.
000108398 700__ $$aMukerji, A.
000108398 700__ $$aDa Silva, O.
000108398 700__ $$aNwaesei, C.
000108398 700__ $$aLee, K.S.
000108398 700__ $$aDunn, M.
000108398 700__ $$aLemyre, B.
000108398 700__ $$aDow, K.
000108398 700__ $$aPelausa, E.
000108398 700__ $$aBarrington, K.
000108398 700__ $$aDrolet, C.
000108398 700__ $$aPiedboeuf, B.
000108398 700__ $$aClaveau, M.
000108398 700__ $$aBeltempo, M.
000108398 700__ $$aBertelle, V.
000108398 700__ $$aMasse, E.
000108398 700__ $$aCanning, R.
000108398 700__ $$aMakary, H.
000108398 700__ $$aOjah, C.
000108398 700__ $$aMonterrosa, L.
000108398 700__ $$aDeshpandey, A.
000108398 700__ $$aAfifi, J.
000108398 700__ $$aKajetanowicz, A.
000108398 700__ $$aAndersson, S.
000108398 700__ $$aTammela, O.
000108398 700__ $$aSankilampi, U.
000108398 700__ $$aSaarela, T.
000108398 700__ $$aPrazad, P.
000108398 700__ $$aNoguchi, A.
000108398 700__ $$aMcWan, K.
000108398 700__ $$aButton, B.
000108398 700__ $$aStratton, W.
000108398 700__ $$aHamvus, A.
000108398 700__ $$aRaghaven, A.
000108398 700__ $$aDerrick, M.
000108398 700__ $$aHadley, R.
000108398 700__ $$aCovert, R.
000108398 700__ $$aLablanc, O.
000108398 700__ $$aWeiss, M.
000108398 700__ $$aBell, A.
000108398 700__ $$aShareef, M.
000108398 700__ $$aSilvestri, J.
000108398 700__ $$aHeymann, E.
000108398 700__ $$aZangen, S.
000108398 700__ $$aSmolkin, T.
000108398 700__ $$aMimouni, F.
000108398 700__ $$aBader, D.
000108398 700__ $$aRothschild, A.
000108398 700__ $$aStrauss, Z.
000108398 700__ $$aFelszer, C.
000108398 700__ $$aOmari, H.
000108398 700__ $$aTov-Friedman, S.E.
000108398 700__ $$aBar-Oz, B.
000108398 700__ $$aFeldman, M.
000108398 700__ $$aSaad, N.
000108398 700__ $$aFlidel-Rimon, O.
000108398 700__ $$aWeisbrod, M.
000108398 700__ $$aLubin, D.
000108398 700__ $$aLitmanovitz, I.
000108398 700__ $$aKugelman, A.
000108398 700__ $$aShinwell, E.
000108398 700__ $$aKlinger, G.
000108398 700__ $$aNijim, Y.
000108398 700__ $$aBin-Nun, A.
000108398 700__ $$aGolan, A.
000108398 700__ $$aMandel, D.
000108398 700__ $$aFleisher-Sheffer, V.
000108398 700__ $$aKohelet, D.
000108398 700__ $$aBakhrakh, L.
000108398 700__ $$aHattori, S.
000108398 700__ $$aShirai, M.
000108398 700__ $$aIshioka, T.
000108398 700__ $$aMori, T.
000108398 700__ $$aAmizuka, T.
000108398 700__ $$aHuchimukai, T.
000108398 700__ $$0(orcid)0000-0002-9641-0324$$aRite Gracia, Segundo$$uUniversidad de Zaragoza
000108398 700__ $$0(orcid)0000-0001-9404-1126$$aVentura Faci, Maria Purificacion$$uUniversidad de Zaragoza
000108398 700__ $$0(orcid)0000-0001-5492-3191$$aSamper Villagrasa, M. Pilar$$uUniversidad de Zaragoza
000108398 7102_ $$11010$$2670$$aUniversidad de Zaragoza$$bDpto. Pediatría Radiol.Med.Fís$$cÁrea Pediatría
000108398 773__ $$g215 (2019), 32-40.e14$$pJ. pediatr.$$tJournal of Pediatrics$$x0022-3476
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000108398 951__ $$a2021-11-15-12:19:35
000108398 980__ $$aARTICLE