000108417 001__ 108417
000108417 005__ 20211115162714.0
000108417 0248_ $$2sideral$$a121556
000108417 037__ $$aART-2020-121556
000108417 041__ $$aeng
000108417 100__ $$aGuzman Prudencio, G.
000108417 245__ $$aCorrelation between the findings in the first post-transplantation Renogram and the allograft renal function twelve months after surgery
000108417 260__ $$c2020
000108417 5060_ $$aAccess copy available to the general public$$fUnrestricted
000108417 5203_ $$aEP-061
Aim/Introduction: To study the correlation between findings in the first renogram post-trasplantation, and the evolution of the renal function of the graft twelve months after surgery.
Materials and Methods: 20-minute duration renogram with [99mTc]Tc-MAG3, performed in the first 72 hours post-kidney transplantation, of patients attended at the Nuclear Medicine Service between January-December of 2018 are reviewed, extracting: a) the concentration angle (CA) that measures the inclination of the ascent section of the concentration phase with respect to the vertical axis (cutoff thershold <40° vs =40°); b) the time, in minutes (Tmax), at which the maximum concentration occurs (<10 vs =10min); and c) the percentage of cortical retention (CR) at the end of the study (<80% vs =80%). These 3 parameters are correlated with renal function at 12 months post-transplantation, through the need or not of dialysis.
Results: A total of 62 renograms were obtained, excluding 7 due to death as a result of intercurrent diseases and 2 due to vascular complications and graft loss, before the first year after surgery. 53 patients, 15 female and 38 male, aged between 20-80 years, were included in the analysis. Functional failure (dialysis) of the graft one year after the transplantation ocurred in 15% (8/53). In patients with CA =40° the probability of failure was 28% (5/18) and in CA <40° 8.6% (3/35), with relative risk (RR) of 3.2. 7/34 (20, 6%) patients incluided in the group with Tmax =10 min were on dialysis one-year after, unlike just 1/19 (5, 3%) if Tmax<10min (RR 3, 8). Among the 37 patients with CR =80%, 8/37 (22%) were dialyzed one year after, while none of the 16 in the group of patients with CR <80% (0% probability if CR <80%). The matching of parameteres CA =40°, Tmax =10 min and CR =80% together do not improve the prediction of dialysis one year after (27%, 5/18). Conclusion: 1. Renogram parameters 72 hours post-transplantation, such as concentration phase angle =40°, time at maximun concentration =10min and percentage of cortical retention =80%, allow recognize a group of patients with greater probability of needing dialysis in the first year after surgery, but they do not are capable of indentify in which specific patients it will occur. 2. The parameter that best predicts the viability of the graft is cortical retention <80%.
000108417 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000108417 590__ $$a9.236$$b2020
000108417 591__ $$aRADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING$$b5 / 134 = 0.037$$c2020$$dQ1$$eT1
000108417 592__ $$a2.313$$b2020
000108417 593__ $$aRadiology, Nuclear Medicine and Imaging$$c2020$$dQ1
000108417 593__ $$aMedicine (miscellaneous)$$c2020$$dQ1
000108417 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000108417 700__ $$aAlvarez Ruiz, S.
000108417 700__ $$aDel Barco Diez Canseco, L. M.
000108417 700__ $$aCalderon Calvente, M.
000108417 700__ $$aNieto Morcillo, L.
000108417 700__ $$0(orcid)0000-0003-0962-7689$$aDe la Cueva Barrao, L.$$uUniversidad de Zaragoza
000108417 700__ $$aFalgas Lacueva, M.
000108417 700__ $$aSangros Sahun, M.
000108417 700__ $$aNavarro Beltran, P.
000108417 700__ $$0(orcid)0000-0002-5512-5885$$aAbos Olivares, D.$$uUniversidad de Zaragoza
000108417 7102_ $$11011$$2770$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Radiol. y Medicina Física
000108417 773__ $$g47, SUPPL 1 (2020), S538-S539$$pEur. J. Nucl. Med. Mol. Imaging$$tEUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING$$x1619-7070
000108417 85641 $$uhttps://link.springer.com/content/pdf/10.1007%2Fs00259-020-04988-4.pdf$$zTexto completo de la revista
000108417 8564_ $$s170025$$uhttps://zaguan.unizar.es/record/108417/files/texto_completo.pdf$$yPostprint
000108417 8564_ $$s3031093$$uhttps://zaguan.unizar.es/record/108417/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000108417 909CO $$ooai:zaguan.unizar.es:108417$$particulos$$pdriver
000108417 951__ $$a2021-11-15-12:20:24
000108417 980__ $$aARTICLE