000109362 001__ 109362
000109362 005__ 20230519145424.0
000109362 0247_ $$2doi$$a10.3390/min12010028
000109362 0248_ $$2sideral$$a125538
000109362 037__ $$aART-2021-125538
000109362 041__ $$aeng
000109362 100__ $$aDiez, Camila
000109362 245__ $$aInfrared spectroscopic analysis of the inorganic components from teeth exposed to psychotherapeutic drugs
000109362 260__ $$c2021
000109362 5060_ $$aAccess copy available to the general public$$fUnrestricted
000109362 5203_ $$aTeeth are unique and complex anatomical organs that can provide relevant data about a person's health, and play an important role in forensic medicine. Teeth are exposed to food, drinks, and the microbiota of the oral cavity; therefore, they have developed a high resistance to localized demineralization. Nevertheless, the continuous demineralization–remineralization cycle present in the oral environment can be influenced by stress, medication, mineralization agents, and other factors such as individual habits, especially diet. In this study, based on attenuated total reflectance Fourier-transform infrared spectroscopy (ATR-FTIR) spectra from tooth samples of 36 patients, several parameters were estimated: the crystallinity index (CI), the phosphate/amide I ratio, and the carbonate/phosphate ratio. In addition, in eight representative samples (six of the root of the tooth and two of the enamel area of the crown), additional characterization by X-ray powder diffraction (XRPD), scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS) was conducted. From the FTIR data, it was observed that the highest CI values were found in patients who smoked. Further, in both root and crown samples, the intensity of the absorption band corresponding to PO43- increased in patients undergoing treatment with psychotherapeutic drugs. On the other hand, the intensity of the absorption band of the amide I group decreased with medical treatment and with the patient's biological age. Moreover, it was found that the remineralization process was more active in enamel than in the root due to direct contact with saliva. Regarding the results obtained from the X-ray powder diffractograms, exposure to psychotherapeutic drugs affected the definition of the peaks corresponding to hydroxyapatite, both in the crown and root samples. Concerning SEM results, qualitative differences in the stratification process in demineralized surfaces were observed, and EDS analyses showed some differences in the Ca/P ratio between pathological samples and control ones, but without clear patterns. The above techniques, in particular ATR-FTIR, showed promise for the investigation of the effect of changes produced in the hydroxyapatite structure in teeth and, consequently, to determine possible strategies in the diagnostic protocol.
000109362 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000109362 590__ $$a2.818$$b2021
000109362 592__ $$a0.522$$b2021
000109362 594__ $$a3.7$$b2021
000109362 591__ $$aGEOCHEMISTRY & GEOPHYSICS$$b42 / 87 = 0.483$$c2021$$dQ2$$eT2
000109362 593__ $$aGeotechnical Engineering and Engineering Geology$$c2021$$dQ2
000109362 591__ $$aMINING & MINERAL PROCESSING$$b8 / 20 = 0.4$$c2021$$dQ2$$eT2
000109362 593__ $$aGeology$$c2021$$dQ2
000109362 591__ $$aMINERALOGY$$b11 / 30 = 0.367$$c2021$$dQ2$$eT2
000109362 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000109362 700__ $$aRojo, María Ángeles
000109362 700__ $$aMartín-Gil, Jesús
000109362 700__ $$0(orcid)0000-0003-2713-2786$$aMartín-Ramos, Pablo$$uUniversidad de Zaragoza
000109362 700__ $$aGarrosa, Manuel
000109362 700__ $$aCórdoba-Diaz, Damián
000109362 7102_ $$15011$$2500$$aUniversidad de Zaragoza$$bDpto. CC.Agrar.y Medio Natural$$cArea Ingeniería Agroforestal
000109362 773__ $$g12, 1 (2021), 28 [17 pp.]$$pMinerals (Basel)$$tMinerals$$x2075-163X
000109362 8564_ $$s3290953$$uhttps://zaguan.unizar.es/record/109362/files/texto_completo.pdf$$yVersión publicada
000109362 8564_ $$s2773124$$uhttps://zaguan.unizar.es/record/109362/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000109362 909CO $$ooai:zaguan.unizar.es:109362$$particulos$$pdriver
000109362 951__ $$a2023-05-18-14:10:57
000109362 980__ $$aARTICLE