000109457 001__ 109457
000109457 005__ 20230519145445.0
000109457 0247_ $$2doi$$a10.1016/j.tet.2021.131926
000109457 0248_ $$2sideral$$a122400
000109457 037__ $$aART-2021-122400
000109457 041__ $$aeng
000109457 100__ $$aMarshall, J.R.
000109457 245__ $$aExpanding the synthetic scope of biocatalysis by enzyme discovery and protein engineering
000109457 260__ $$c2021
000109457 5060_ $$aAccess copy available to the general public$$fUnrestricted
000109457 5203_ $$aDespite the growing impact of enzyme catalysis in industrial chemistry, the full potential of this technology is yet to be unlocked. Accessing new chemistries and expanding the scope of existing reactions is necessary in order to make biocatalysis a pivotal technology in the manufacturing of chemicals across the whole industrial spectrum. This review highlights how the biocatalytic toolbox for synthetic chemistry has recently been expanded by extending the scope of industrially relevant reactions, and the addition of new reactions via enzyme discovery or protein engineering.
000109457 536__ $$9info:eu-repo/grantAgreement/ES/DGA-FSE/E07-20R$$9info:eu-repo/grantAgreement/EC/H2020/742987/EU/Biocatalytic Amine Synthesis via Hydrogen Borrowing/BIO-H-BORROW$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 742987-BIO-H-BORROW
000109457 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000109457 590__ $$a2.388$$b2021
000109457 592__ $$a0.507$$b2021
000109457 594__ $$a4.5$$b2021
000109457 591__ $$aCHEMISTRY, ORGANIC$$b25 / 57 = 0.439$$c2021$$dQ2$$eT2
000109457 593__ $$aOrganic Chemistry$$c2021$$dQ2
000109457 593__ $$aBiochemistry$$c2021$$dQ2
000109457 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000109457 700__ $$0(orcid)0000-0002-3364-1512$$aMangas-Sanchez, J.$$uUniversidad de Zaragoza
000109457 700__ $$aTurner, N.J.
000109457 7102_ $$12013$$2765$$aUniversidad de Zaragoza$$bDpto. Química Orgánica$$cÁrea Química Orgánica
000109457 773__ $$g82, 131926 (2021), [13 pp]$$pTetrahedron$$tTETRAHEDRON$$x0040-4020
000109457 8564_ $$s996267$$uhttps://zaguan.unizar.es/record/109457/files/texto_completo.pdf$$yPostprint
000109457 8564_ $$s2285882$$uhttps://zaguan.unizar.es/record/109457/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000109457 909CO $$ooai:zaguan.unizar.es:109457$$particulos$$pdriver
000109457 951__ $$a2023-05-18-14:37:08
000109457 980__ $$aARTICLE