000109543 001__ 109543
000109543 005__ 20240122154815.0
000109543 0247_ $$2doi$$a10.3390/nu13061838
000109543 0248_ $$2sideral$$a127165
000109543 037__ $$aART-2021-127165
000109543 041__ $$aeng
000109543 100__ $$0(orcid)0000-0002-8100-5596$$aMartínez-Beamonte, R.$$uUniversidad de Zaragoza
000109543 245__ $$aDietary avian proteins are comparable to soybean proteins on the atherosclerosis development and fatty liver disease in apoe-deficient mice
000109543 260__ $$c2021
000109543 5060_ $$aAccess copy available to the general public$$fUnrestricted
000109543 5203_ $$aBackground and aim: The type and amount of dietary protein has become a topic of re-newed interest in light of their involvement in metabolic diseases, atherosclerosis and thrombosis. However, little attention has been devoted to the effect of avian proteins despite their wide human consumption. The aim was to investigate the influence of chicken and turkey as sources of protein compared with that of soybean on atherosclerosis and fatty liver disease. Methods and results: To this purpose, male and female Apoe-deficient were fed purified Western diets differing in their protein sources for 12 weeks. After this period, blood, liver, aortic tree and heart base samples were taken for analyses of plasma lipids and atherosclerosis. Plasma triglycerides, non-esterified fatty acids, esterified cholesterol levels and radical oxygen species in lipoproteins changed depending on the diet and sex. Females consuming the turkey protein-containing diet showed decreased athero-sclerotic foci, as evidenced by the en face atherosclerosis analyses. The presence of macrophages and smooth muscle cells in plaques were not modified, and no changes were observed in hepatic lipid droplets in the studied groups either. Paraoxonase activity was higher in the group consuming turkey protein without sex differences, but only in females, it was significantly associated with aor-tic lesion areas. Conclusions: Compared to soybean protein, the consumption of avian proteins depending on sex resulted in similar or lower atherosclerosis development and comparable hepatic steatosis.
000109543 536__ $$9info:eu-repo/grantAgreement/ES/CIBERObn/CB06-03-1012$$9info:eu-repo/grantAgreement/ES/DGA/B16-20R$$9info:eu-repo/grantAgreement/ES/MICINN AEI/PID2019-104915RB-I00$$9info:eu-repo/grantAgreement/ES/MICINN/SAF2016-75441-R
000109543 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000109543 590__ $$a6.706$$b2021
000109543 592__ $$a1.287$$b2021
000109543 594__ $$a7.9$$b2021
000109543 591__ $$aNUTRITION & DIETETICS$$b15 / 90 = 0.167$$c2021$$dQ1$$eT1
000109543 593__ $$aNutrition and Dietetics$$c2021$$dQ1
000109543 593__ $$aFood Science$$c2021$$dQ1
000109543 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000109543 700__ $$0(orcid)0000-0002-9023-741X$$aSánchez-Marco, J.
000109543 700__ $$aLázaro, G.
000109543 700__ $$aBarco, M.
000109543 700__ $$aHerrero-Continente, T.
000109543 700__ $$aSerrano-Megías, M.
000109543 700__ $$aBotaya, D.
000109543 700__ $$0(orcid)0000-0003-1197-4276$$aArnal, C.$$uUniversidad de Zaragoza
000109543 700__ $$0(orcid)0000-0002-8442-8041$$aBarranquero, C.
000109543 700__ $$0(orcid)0000-0002-5841-0462$$aSurra, J.C.$$uUniversidad de Zaragoza
000109543 700__ $$0(orcid)0000-0002-8251-8457$$aOsada, J.$$uUniversidad de Zaragoza
000109543 700__ $$0(orcid)0000-0002-0108-1004$$aNavarro, M.A.$$uUniversidad de Zaragoza
000109543 7102_ $$11009$$2773$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Sanidad Animal
000109543 7102_ $$12008$$2700$$aUniversidad de Zaragoza$$bDpto. Produc.Animal Cienc.Ali.$$cÁrea Producción Animal
000109543 7102_ $$11002$$2060$$aUniversidad de Zaragoza$$bDpto. Bioq.Biolog.Mol. Celular$$cÁrea Bioquímica y Biolog.Mole.
000109543 7102_ $$11002$$2050$$aUniversidad de Zaragoza$$bDpto. Bioq.Biolog.Mol. Celular$$cÁrea Biología Celular
000109543 773__ $$g13, 6 (2021), 1838 [14 pp.]$$pNutrients$$tNutrients$$x2072-6643
000109543 8564_ $$s1337191$$uhttps://zaguan.unizar.es/record/109543/files/texto_completo.pdf$$yVersión publicada
000109543 8564_ $$s2735340$$uhttps://zaguan.unizar.es/record/109543/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000109543 909CO $$ooai:zaguan.unizar.es:109543$$particulos$$pdriver
000109543 951__ $$a2024-01-22-15:40:21
000109543 980__ $$aARTICLE