000110662 001__ 110662 000110662 005__ 20220817094823.0 000110662 0247_ $$2doi$$a10.24875/RECICE.M21000220 000110662 0248_ $$2sideral$$a127455 000110662 037__ $$aART-2021-127455 000110662 041__ $$aeng 000110662 100__ $$aCepas-Guillén, P. L. 000110662 245__ $$aOutcomes of nonagenarians after transcatheter aortic valve implantation 000110662 260__ $$c2021 000110662 5060_ $$aAccess copy available to the general public$$fUnrestricted 000110662 5203_ $$aIntroduction and objectives: Nonagenarians are a fast-growing age group among cardiovascular patients, especially with aortic stenosis, but data about their prognosis after transcatheter aortic valve implantation (TAVI) is scarce. The objective of our study is to analyze the baseline characteristics of nonagenarians treated with TAVI and determine whether age = 90 years is associated with a worse prognosis compared to non-nonagenarian patients. Methods: We included all patients =75 years enrolled in the multicenter prospective Spanish TAVI registry between 2009 and 2018. Patients < 75 years were excluded. Results: A total of 8073 elderly patients (= 75 years) from 46 Spanish centers were enrolled in the Spanish TAVI registry; 7686 were between = 75 and < 90 years old (95.2%), and 387 were nonagenarian patients (4.79%). A gradual increase of nonagenarians was observed. The transfemoral access was used in 91.6% of the cases, predominantly among the nonagenarian patients (91.4% vs 95.1%, P = .01). Nonagenarians were more likely to die during their hospital stay (4.3% vs 7.0% among nonagenarians, P = .01). However, no difference was seen in the all-cause mortality rates reported at the 1-year follow-up (8.8% vs 11.3%, P =.07). In the multivariate analysis, age = 90 years was not independently associated with a higher adjusted all-cause mortality rate (HR, 1.37, 95%CI, 0.91–1.97, P = .14). The baseline creatinine levels, and the in-hospital bleeding complications were all associated with a worse long-term prognosis in nonagenarians treated with TAVI. Conclusions: Nonagenarians are a very high-risk and growing population with severe AS in whom TAVI may be a safe and effective strategy. Careful patient selection by the TAVI heart team is mandatory to achieve maximum efficiency in this population where the baseline kidney function and bleeding complications may determine the long-term prognosis after TAVI. © 2021 Sociedad Española de Cardiología. Published by Permanyer Publications. 000110662 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/ 000110662 594__ $$a3.0$$b2021 000110662 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000110662 700__ $$aRegueiro, A. 000110662 700__ $$aSanmiguel Cervera, D. 000110662 700__ $$aBlanco Mata, R. 000110662 700__ $$aOteo J. F. 000110662 700__ $$aAmat-Santos, I. 000110662 700__ $$aTen, F. 000110662 700__ $$aNogales, J. M. 000110662 700__ $$aFernández-Nofrerías, E. 000110662 700__ $$aMainar, V. 000110662 700__ $$aLasa-Larraya, G. 000110662 700__ $$aAndraka, L. 000110662 700__ $$aBaz-Alonso, J. A. 000110662 700__ $$0(orcid)0000-0002-3413-6024$$aFerrer, M. C. 000110662 700__ $$aPinar, E. 000110662 700__ $$aRomaguera, R. 000110662 700__ $$aCuellas Ramón, C. 000110662 700__ $$aAlfonso, F. 000110662 700__ $$aUrbano-Carrillo, C. A. 000110662 700__ $$aGarcía-Blas, S. 000110662 700__ $$aPiñero, A. 000110662 700__ $$aAlbarrán, A. 000110662 700__ $$aRuiz-Salmerón, R. 000110662 700__ $$aMoreu, J. 000110662 700__ $$aGil Albarova, Ó. 000110662 700__ $$aMelero, J. M. 000110662 700__ $$aHeredia Cambra, T. 000110662 700__ $$aFreixa, X. 000110662 700__ $$aSabaté, M. 000110662 773__ $$g3, 4 (2021), 250-257$$pREC Interv. cardiol.$$tREC, Interventional cardiology$$x2604-7306 000110662 8564_ $$s375853$$uhttps://zaguan.unizar.es/record/110662/files/texto_completo.pdf$$yVersión publicada 000110662 8564_ $$s2961243$$uhttps://zaguan.unizar.es/record/110662/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000110662 909CO $$ooai:zaguan.unizar.es:110662$$particulos$$pdriver 000110662 951__ $$a2022-08-17-09:36:37 000110662 980__ $$aARTICLE