000110760 001__ 110760 000110760 005__ 20220223124038.0 000110760 0247_ $$2doi$$a10.1002/ppul.24816 000110760 0248_ $$2sideral$$a117694 000110760 037__ $$aART-2020-117694 000110760 041__ $$aeng 000110760 100__ $$0(orcid)0000-0002-8880-6580$$aSerrano-Casorran, Carolina$$uUniversidad de Zaragoza 000110760 245__ $$aA new airway spiral stent designed to maintain airway architecture with an atraumatic removal after full epithelization - Research of feasibility and viability in canine patients with tracheomalacia 000110760 260__ $$c2020 000110760 5060_ $$aAccess copy available to the general public$$fUnrestricted 000110760 5203_ $$aObjective: Surgical management of tracheomalacia is a challenge, with current treatments still presenting numerous complications. In the field of veterinary medicine, this same pathology is present in a significant number of dogs. For this reason, we present an experimental clinical trial performed on canines with tracheobronchomalacia, using a new atraumatic removable tracheal spiral stent (SS). Both implantation procedure and clinical improvement have been analyzed in this study.Methods: In this study, four small dogs, a mean weight of 4.89 kg and body condition scores IV‐V, were included. SS was implanted by two different surgical approaches. Image and clinical follow‐up have been performed during 90 days. Symptoms were evaluated from 1 to 10 every week. Results: This study achieved 100% technical and clinical success. Median tracheal diameters were as follows: cervical 10.85 (3.3), inlet 7.75 (2.1), and carina 7.75 (1.9) mm, and length was 77.5 (26) mm. A 12 × 10 × 100‐mm SS was implanted in all cases. Goose honk cough punctuation improved from 8 to 1; also, there were important changes in exercise intolerance, a mean weight loss of 8.76%. The values of modified Karnofsky scale varied from 50 (20) before surgery to 90 (10) after 30 days of surgery. Neither granuloma tissue nor fractures of the prosthesis was observed.Conclusion: The results in dogs are promising, and a new therapeutic alternative seems to be available for veterinarian field. The similarity of this disease between dogs and newborns suggests that this SS design can also be useful for human trials. 000110760 536__ $$9info:eu-repo/grantAgreement/ES/DGA/B36-17R 000110760 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/ 000110760 590__ $$a3.039$$b2020 000110760 591__ $$aPEDIATRICS$$b36 / 129 = 0.279$$c2020$$dQ2$$eT1 000110760 591__ $$aRESPIRATORY SYSTEM$$b36 / 64 = 0.562$$c2020$$dQ3$$eT2 000110760 592__ $$a0.865$$b2020 000110760 593__ $$aPulmonary and Respiratory Medicine$$c2020$$dQ1 000110760 593__ $$aPediatrics, Perinatology and Child Health$$c2020$$dQ1 000110760 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion 000110760 700__ $$0(orcid)0000-0001-8537-0585$$aLopez-Minguez, Sandra$$uUniversidad de Zaragoza 000110760 700__ $$0(orcid)0000-0003-3880-3821$$aRodriguez-Zapater, Sergio$$uUniversidad de Zaragoza 000110760 700__ $$0(orcid)0000-0001-6178-9891$$aBonastre, Cristina$$uUniversidad de Zaragoza 000110760 700__ $$0(orcid)0000-0002-0113-5121$$aGuirola, Jose A.$$uUniversidad de Zaragoza 000110760 700__ $$0(orcid)0000-0002-5618-7519$$aGregorio Ariza, Miguel Ángel de$$uUniversidad de Zaragoza 000110760 7102_ $$11011$$2770$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Radiol. y Medicina Física 000110760 7102_ $$11009$$2773$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Sanidad Animal 000110760 7102_ $$11009$$2617$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Medicina y Cirugía Animal 000110760 773__ $$g55, 7 (2020), 1757-1764$$pPediatr. pulmonol.$$tPEDIATRIC PULMONOLOGY$$x8755-6863 000110760 8564_ $$s392879$$uhttps://zaguan.unizar.es/record/110760/files/texto_completo.pdf$$yPostprint 000110760 8564_ $$s1200458$$uhttps://zaguan.unizar.es/record/110760/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint 000110760 909CO $$ooai:zaguan.unizar.es:110760$$particulos$$pdriver 000110760 951__ $$a2022-02-23-11:08:18 000110760 980__ $$aARTICLE