000111667 001__ 111667 000111667 005__ 20240319080953.0 000111667 0247_ $$2doi$$a10.1016/j.exger.2021.111656 000111667 0248_ $$2sideral$$a127798 000111667 037__ $$aART-2022-127798 000111667 041__ $$aeng 000111667 100__ $$0(orcid)0000-0002-1113-9169$$aPérez-Lasierra, J. L.$$uUniversidad de Zaragoza 000111667 245__ $$aAssociation of physical activity levels and prevalence of major degenerative diseases: Evidence from the national health and nutrition examination survey (NHANES) 1999–2018 000111667 260__ $$c2022 000111667 5060_ $$aAccess copy available to the general public$$fUnrestricted 000111667 5203_ $$aObjectives: Degenerative diseases are associated with lower healthy life expectancy and higher mortality. Physical activity (PA) has demonstrated a fundamental role in the prevention and control of several pathologies associated to the aging process. The aim of this study was to analyze the association of PA with the prevalence of sarcopenia, osteoporosis and osteoarthritis in non-institutionalized American population. Methods: Cross-sectional study carried out in participants aged ≥50 years from the 1999–2018 National Health and Nutrition Examination Survey (NHANES). Sarcopenia was defined using appendicular lean mass adjusted for body mass index (ALM:BMI; men <0.789 kg/m2, women <0.512 kg/m2). Osteoporosis was defined as bone mineral density T-score ≤−2.5 of femur neck. Osteoarthritis and PA were self-reported, and total PA was used to classify participants in groups. The Odds Ratios among the different PA levels for each disease were examined. Results: Performing at least 150 MET-min/week of PA was associated with reduced odds for sarcopenia; performing >1800 MET-min/week was associated with reduced odds for osteoporosis; and performing 150–1800 MET-min/week of PA was associated with reduced odds for osteoarthritis after adjust the results by several confounders. Conclusions: The benefits of PA in sarcopenia, osteoporosis, and osteoarthritis prevention are evident among Americans aged ≥50 years. 000111667 536__ $$9info:eu-repo/grantAgreement/ES/MECD/FPU16-02539 000111667 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/ 000111667 590__ $$a3.9$$b2022 000111667 591__ $$aGERIATRICS & GERONTOLOGY$$b27 / 54 = 0.5$$c2022$$dQ2$$eT2 000111667 593__ $$aCell Biology$$c2022$$dQ2 000111667 593__ $$aBiochemistry$$c2022$$dQ2 000111667 593__ $$aMolecular Biology$$c2022$$dQ2 000111667 593__ $$aEndocrinology$$c2022$$dQ2 000111667 593__ $$aGenetics$$c2022$$dQ2 000111667 593__ $$aAging$$c2022$$dQ3 000111667 594__ $$a6.7$$b2022 000111667 592__ $$a0.937$$b2022 000111667 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000111667 700__ $$0(orcid)0000-0002-7215-6931$$aCasajus, J. A.$$uUniversidad de Zaragoza 000111667 700__ $$0(orcid)0000-0002-1132-5906$$aGonzález de Agüero, A.$$uUniversidad de Zaragoza 000111667 700__ $$0(orcid)0000-0003-0604-5042$$aMoreno Franco, B.$$uUniversidad de Zaragoza 000111667 7102_ $$11006$$2245$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Educación Física y Depor. 000111667 7102_ $$11011$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Medic.Prevent.Salud Públ. 000111667 773__ $$g158 (2022), 111656 [7 pp.]$$pExp. gerontol.$$tExperimental gerontology$$x0531-5565 000111667 8564_ $$s611723$$uhttps://zaguan.unizar.es/record/111667/files/texto_completo.pdf$$yVersión publicada 000111667 8564_ $$s2380780$$uhttps://zaguan.unizar.es/record/111667/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000111667 909CO $$ooai:zaguan.unizar.es:111667$$particulos$$pdriver 000111667 951__ $$a2024-03-18-13:15:47 000111667 980__ $$aARTICLE