000112010 001__ 112010 000112010 005__ 20240319080949.0 000112010 0247_ $$2doi$$a10.3390/catal12020167 000112010 0248_ $$2sideral$$a127720 000112010 037__ $$aART-2022-127720 000112010 041__ $$aeng 000112010 100__ $$0(orcid)0000-0002-1791-0188$$aBonet-Aleta, Javier$$uUniversidad de Zaragoza 000112010 245__ $$aEngineered nanostructured photocatalysts for cancer therapy 000112010 260__ $$c2022 000112010 5060_ $$aAccess copy available to the general public$$fUnrestricted 000112010 5203_ $$aThe present review aims at highlighting recent advances in the development of photocatalysts devoted to cancer therapy applications. We pay especial attention to the engineering aspects of different nanomaterials including inorganic semiconductors, organic-based nanostructures, noble metal-based systems or synergistic hybrid heterostructures. Furthermore, we also explore and correlate structural and optical properties with their photocatalytic capability to successfully performing in cancer-related therapies. We have made an especial emphasis to introduce current alternatives to organic photosensitizers (PSs) in photodynamic therapy (PDT), where the effective generation of reactive oxidative species (ROS) is pivotal to boost the efficacy of the treatment. We also overview current efforts in other photocatalytic strategies to tackle cancer based on photothermal treatment, starvation therapy, oxidative stress unbalance via glutathione (GSH) depletion, biorthogonal catalysis or local relief of hypoxic conditions in tumor microenvironments (TME). 000112010 536__ $$9info:eu-repo/grantAgreement/ES/MCIU/FPU18/04618 000112010 540__ $$9info:eu-repo/semantics/openAccess$$aby-sa$$uhttp://creativecommons.org/licenses/by-sa/3.0/es/ 000112010 590__ $$a3.9$$b2022 000112010 592__ $$a0.69$$b2022 000112010 591__ $$aCHEMISTRY, PHYSICAL$$b71 / 161 = 0.441$$c2022$$dQ2$$eT2 000112010 593__ $$aPhysical and Theoretical Chemistry$$c2022$$dQ2 000112010 593__ $$aCatalysis$$c2022$$dQ2 000112010 594__ $$a6.3$$b2022 000112010 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000112010 700__ $$0(orcid)0000-0003-4874-6672$$aGarcia-Peiro, Jose I.$$uUniversidad de Zaragoza 000112010 700__ $$0(orcid)0000-0002-4546-4111$$aHueso, Jose L.$$uUniversidad de Zaragoza 000112010 7102_ $$15005$$2555$$aUniversidad de Zaragoza$$bDpto. Ing.Quím.Tecnol.Med.Amb.$$cÁrea Ingeniería Química 000112010 773__ $$g12, 2 (2022), 167 [28 pp.]$$pCatalysts$$tCatalysts$$x2073-4344 000112010 8564_ $$s8645589$$uhttps://zaguan.unizar.es/record/112010/files/texto_completo.pdf$$yVersión publicada 000112010 8564_ $$s2805803$$uhttps://zaguan.unizar.es/record/112010/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000112010 909CO $$ooai:zaguan.unizar.es:112010$$particulos$$pdriver 000112010 951__ $$a2024-03-18-12:52:58 000112010 980__ $$aARTICLE