000112066 001__ 112066
000112066 005__ 20240319080959.0
000112066 0247_ $$2doi$$a10.3390/biomedicines10010088
000112066 0248_ $$2sideral$$a127728
000112066 037__ $$aART-2022-127728
000112066 041__ $$aeng
000112066 100__ $$aBoned-Murillo, Ana
000112066 245__ $$aOptical coherence tomography angiography in diabetic patients: a systematic review
000112066 260__ $$c2022
000112066 5060_ $$aAccess copy available to the general public$$fUnrestricted
000112066 5203_ $$aBackground: Diabetic retinopathy (DR) is the leading cause of legal blindness in the working population in developed countries. Optical coherence tomography (OCT) angiography (OCTA) has risen as an essential tool in the diagnosis and control of diabetic patients, with and without DR, allowing visualisation of the retinal and choroidal microvasculature, their qualitative and quantitative changes, the progression of vascular disease, quantification of ischaemic areas, and the detection of preclinical changes. The aim of this article is to analyse the current applications of OCTA and provide an updated overview of them in the evaluation of DR. Methods: A systematic literature search was performed in PubMed and Embase, including the keywords “OCTA” OR “OCT angiography” OR “optical coherence tomography angiography” AND “diabetes” OR “diabetes mellitus” OR “diabetic retinopathy” OR “diabetic maculopathy” OR “diabetic macular oedema” OR “diabetic macular ischaemia”. Of the 1456 studies initially identified, 107 studies were screened after duplication, and those articles that did not meet the selection criteria were removed. Finally, after looking for missing data, we included 135 studies in this review. Results: We present the common and distinctive findings in the analysed papers after the literature search including the diagnostic use of OCTA in diabetes mellitus (DM) patients. We describe previous findings in retinal vascularization, including microaneurysms, foveal avascular zone (FAZ) changes in both size and morphology, changes in vascular perfusion, the appearance of retinal microvascular abnormalities or new vessels, and diabetic macular oedema (DME) and the use of deep learning technology applied to this disease. Conclusion: OCTA findings enable the diagnosis and follow-up of DM patients, including those with no detectable lesions with other devices. The evaluation of retinal and choroidal plexuses using OCTA is a fundamental tool for the diagnosis and prognosis of DR.
000112066 536__ $$9info:eu-repo/grantAgreement/ES/DGA/B08-20R$$9info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI20-00740$$9info:eu-repo/grantAgreement/ES/MEC/FPU18-02964
000112066 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000112066 590__ $$a4.7$$b2022
000112066 592__ $$a0.897$$b2022
000112066 591__ $$aPHARMACOLOGY & PHARMACY$$b68 / 278 = 0.245$$c2022$$dQ1$$eT1
000112066 593__ $$aMedicine (miscellaneous)$$c2022$$dQ1
000112066 591__ $$aBIOCHEMISTRY & MOLECULAR BIOLOGY$$b92 / 285 = 0.323$$c2022$$dQ2$$eT1
000112066 593__ $$aBiochemistry, Genetics and Molecular Biology (miscellaneous)$$c2022$$dQ2
000112066 591__ $$aMEDICINE, RESEARCH & EXPERIMENTAL$$b54 / 136 = 0.397$$c2022$$dQ2$$eT2
000112066 594__ $$a3.7$$b2022
000112066 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000112066 700__ $$aAlbertos-Arranz, Henar
000112066 700__ $$aDiaz-Barreda, María Dolores
000112066 700__ $$0(orcid)0000-0003-2710-1875$$aOrduna-Hospital, Elvira$$uUniversidad de Zaragoza
000112066 700__ $$0(orcid)0000-0002-5621-1937$$aSánchez-Cano, Ana$$uUniversidad de Zaragoza
000112066 700__ $$0(orcid)0000-0002-2914-2593$$aFerreras, Antonio$$uUniversidad de Zaragoza
000112066 700__ $$aCuenca, Nicolás
000112066 700__ $$0(orcid)0000-0003-0349-9997$$aPinilla, Isabel$$uUniversidad de Zaragoza
000112066 7102_ $$11013$$2646$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Oftalmología
000112066 7102_ $$12002$$2647$$aUniversidad de Zaragoza$$bDpto. Física Aplicada$$cÁrea Óptica
000112066 773__ $$g10, 1 (2022), 88 [25 pp.]$$tBiomedicines$$x2227-9059
000112066 8564_ $$s3827056$$uhttps://zaguan.unizar.es/record/112066/files/texto_completo.pdf$$yVersión publicada
000112066 8564_ $$s2677039$$uhttps://zaguan.unizar.es/record/112066/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000112066 909CO $$ooai:zaguan.unizar.es:112066$$particulos$$pdriver
000112066 951__ $$a2024-03-18-13:55:34
000112066 980__ $$aARTICLE