000112163 001__ 112163
000112163 005__ 20230526092854.0
000112163 0247_ $$2doi$$a10.1016/j.ijfoodmicro.2021.109462
000112163 0248_ $$2sideral$$a128295
000112163 037__ $$aART-2021-128295
000112163 041__ $$aeng
000112163 100__ $$0(orcid)0000-0002-4027-5637$$aGuillén, Silvia$$uUniversidad de Zaragoza
000112163 245__ $$aRelationship between growth ability, virulence, and resistance to food-processing related stresses in non-typhoidal Salmonellae
000112163 260__ $$c2021
000112163 5060_ $$aAccess copy available to the general public$$fUnrestricted
000112163 5203_ $$aThe ability of Salmonella to resist and adapt to harsh conditions is one of the major features that have made this microorganism such a relevant health hazard. However, the impact of these resistance responses on other aspects of Salmonella physiology, such as virulence and growth ability, is still not fully understood. The objective of this study was to determine the maximum growth rates (in three different media), virulence (adhesion and invasion of Caco-2 cells), and other phenotypic characteristics (biofilm-forming ability and antimicrobial resistance) of 23 Salmonella strains belonging to different serovars, and to compare them with their previously determined stress resistance parameters. Significant differences (p < 0.05) in growth rates, virulence, and biofilm-forming ability were found among the 23 strains studied. Nevertheless, whereas less than 3-fold change between the lowest and the highest growth rate was observed, the percentage of cells capable of invading Caco-2 cells varied more than 100-fold, that to form biofilms more than 30-fold, and the antibiotic MICs varied up to 512-fold, among the different strains. Results indicate that those strains with the highest cell adhesion ability were not always the most invasive ones and suggest that, in general terms, a higher stress resistance did not imply a reduced growth ability (rate). Similarly, no association between stress resistance and biofilm formation ability (except for acid stress) or antibiotic resistance (with minor exceptions) was found. Our data also suggest that, in Salmonella, acid stress resistance would be associated with virulence, since a positive correlation of that trait with adhesion and a negative correlation with invasion was found. This study contributes to a better understanding of the physiology of Salmonella and the relationship between bacterial stress resistance, growth ability, and virulence. It also provides new data regarding intra-specific variability of a series of phenotypic characteristics of Salmonella that are relevant from the food safety perspective.
000112163 536__ $$9info:eu-repo/grantAgreement/ES/MINECO/AGL2017-84084-R
000112163 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000112163 590__ $$a5.911$$b2021
000112163 592__ $$a0.997$$b2021
000112163 594__ $$a9.4$$b2021
000112163 591__ $$aFOOD SCIENCE & TECHNOLOGY$$b31 / 144 = 0.215$$c2021$$dQ1$$eT1
000112163 593__ $$aFood Science$$c2021$$dQ1
000112163 591__ $$aMICROBIOLOGY$$b36 / 138 = 0.261$$c2021$$dQ2$$eT1
000112163 593__ $$aMicrobiology$$c2021$$dQ1
000112163 593__ $$aMedicine (miscellaneous)$$c2021$$dQ1
000112163 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000112163 700__ $$aMarcén, María
000112163 700__ $$aFau, Ester
000112163 700__ $$0(orcid)0000-0002-7971-4828$$aMañas, Pilar$$uUniversidad de Zaragoza
000112163 700__ $$0(orcid)0000-0002-5049-3646$$aCebrián, Guillermo$$uUniversidad de Zaragoza
000112163 7102_ $$12008$$2780$$aUniversidad de Zaragoza$$bDpto. Produc.Animal Cienc.Ali.$$cÁrea Tecnología de Alimentos
000112163 773__ $$g361 (2021), 109462 [13 p.]$$pInt. j. food microbiol.$$tINTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY$$x0168-1605
000112163 8564_ $$s2245719$$uhttps://zaguan.unizar.es/record/112163/files/texto_completo.pdf$$yVersión publicada
000112163 8564_ $$s2650073$$uhttps://zaguan.unizar.es/record/112163/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000112163 909CO $$ooai:zaguan.unizar.es:112163$$particulos$$pdriver
000112163 951__ $$a2023-05-26-08:13:59
000112163 980__ $$aARTICLE