112475 20230519145433.0 doi 10.1093/jas/skab316 sideral 127516 ART-2021-127516 eng Perdomo-González, D.I. Genetic inbreeding depression load for fertility traits in Pura Raza Española mares 2021 Access copy available to the general public Unrestricted Fertility is a key factor in the economic success of horse farms. However, it has received little attention due to the difficulty of measuring fertility objectively. Since its studbook creation (1912), the Pura Raza Española (PRE) breed has been a closed population and become high in-bred resulting in inbreeding depression (poor phenotypic values). Nevertheless, heterogeneous effects of inbreeding depression have been detected among founders and nonfounders. The aims of this study were (1) to analyze the genetic parameters for reproductive traits in mares of the PRE horse breed and (2) to estimate, for the first time, the inbreeding depression load associated with common ancestors of the breed. A total of 22, 799 mares were analyzed. Heritability estimates ranged from 0.05 (interval between first and second foaling) to 0.16 (age at first foaling), whereas inbreeding depression load ratios ranged from 0.06 (parturition efficiency at 6th foaling) to 0.17 (age at first foaling), for a partial inbreeding coefficient of 10%. Although heritability is related to the variability expressed in the population, inbreeding depression load ratios measure the potential variability, whether expressed in the population or not. Most correlations between additive and inbreeding depression load genetic values were significant (P < 0.001) and of low to moderate magnitude. Our results confirm that individual inbreeding depression loads allow us to select horses that have a genetic value resistant to the deleterious effects of inbreeding. © The Author(s) 2021. Published by Oxford University Press on behalf of the American Society of Animal Science. info:eu-repo/grantAgreement/ES/MINECO/AGL2017-84217-P info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 3.338 2021 AGRICULTURE, DAIRY & ANIMAL SCIENCE 10 / 63 = 0.159 2021 Q1 T1 0.854 2021 Animal Science and Zoology 2021 Q1 Medicine (miscellaneous) 2021 Q1 Food Science 2021 Q1 4.7 2021 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Molina, A. Sánchez-Guerrero, M.J. Bartolomé, E. Varona, L. Universidad de Zaragoza (orcid)0000-0001-6256-5478 Valera, M. 1001 420 Universidad de Zaragoza Dpto. Anatom.,Embri.Genét.Ani. Área Genética 99, 12 (2021), skab316 [10 pp.] J. anim. sci. Journal of Animal Science 0021-8812 15861373 http://zaguan.unizar.es/record/112475/files/texto_completo.pdf Versión publicada 2687189 http://zaguan.unizar.es/record/112475/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:112475 articulos driver 2023-05-18-14:20:24 ARTICLE