000112740 001__ 112740
000112740 005__ 20240319080951.0
000112740 0247_ $$2doi$$a10.3390/catal12010101
000112740 0248_ $$2sideral$$a128354
000112740 037__ $$aART-2022-128354
000112740 041__ $$aeng
000112740 100__ $$0(orcid)0000-0002-0904-9180$$aArdevines, Sandra$$uUniversidad de Zaragoza
000112740 245__ $$aHorizons in Asymmetric Organocatalysis: En Route to the Sustainability and New Applications
000112740 260__ $$c2022
000112740 5060_ $$aAccess copy available to the general public$$fUnrestricted
000112740 5203_ $$aNowadays, the development of new enantioselective processes is highly relevant in chemistry due to the relevance of chiral compounds in biomedicine (mainly drugs) and in other fields, such as agrochemistry, animal feed, and flavorings. Among them, organocatalytic methods have become an efficient and sustainable alternative since List and MacMillan pioneering contributions were published in 2000. These works established the term asymmetric organocatalysis to label this area of research, which has grown exponentially over the last two decades. Since then, the scientific community has attended to the discovery of a plethora of organic reactions and transformations carried out with excellent results in terms of both reactivity and enantioselectivity. Looking back to earlier times, we can find in the literature a few examples where small organic molecules and some natural products could act as effective catalysts. However, with the birth of this type of catalysis, new chemical architectures based on amines, thioureas, squaramides, cinchona alkaloids, quaternary ammonium salts, carbenes, guanidines and phosphoric acids, among many others, have been devel-oped. These organocatalysts have provided a broad range of activation modes that allow privileged interactions between catalysts and substrates for the preparation of compounds with high added value in an enantioselective way. Here, we briefly cover the history of this chemistry, from our point of view, including our beginnings, how the field has evolved during these years of research, and the road ahead. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
000112740 536__ $$9info:eu-repo/grantAgreement/ES/AEI/PID2020-117455GB-I00$$9info:eu-repo/grantAgreement/ES/DGA-FSE/E07-20R
000112740 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000112740 590__ $$a3.9$$b2022
000112740 592__ $$a0.69$$b2022
000112740 591__ $$aCHEMISTRY, PHYSICAL$$b71 / 161 = 0.441$$c2022$$dQ2$$eT2
000112740 593__ $$aPhysical and Theoretical Chemistry$$c2022$$dQ2
000112740 593__ $$aCatalysis$$c2022$$dQ2
000112740 594__ $$a6.3$$b2022
000112740 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000112740 700__ $$0(orcid)0000-0001-6832-8983$$aMarqués-López, Eugenia$$uUniversidad de Zaragoza
000112740 700__ $$0(orcid)0000-0002-5244-9569$$aPérez Herrera, Raquel
000112740 7102_ $$12013$$2765$$aUniversidad de Zaragoza$$bDpto. Química Orgánica$$cÁrea Química Orgánica
000112740 773__ $$g12, 1 (2022), [13 pp.]$$pCatalysts$$tCatalysts$$x2073-4344
000112740 8564_ $$s3971096$$uhttps://zaguan.unizar.es/record/112740/files/texto_completo.pdf$$yVersión publicada
000112740 8564_ $$s2730121$$uhttps://zaguan.unizar.es/record/112740/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000112740 909CO $$ooai:zaguan.unizar.es:112740$$particulos$$pdriver
000112740 951__ $$a2024-03-18-13:04:31
000112740 980__ $$aARTICLE