000117260 001__ 117260 000117260 005__ 20240319081011.0 000117260 0247_ $$2doi$$a10.3390/nu14112302 000117260 0248_ $$2sideral$$a128618 000117260 037__ $$aART-2022-128618 000117260 041__ $$aeng 000117260 100__ $$0(orcid)0000-0002-5089-7819$$aSubías-Perié, Jorge$$uUniversidad de Zaragoza 000117260 245__ $$aPrevalence of Metabolic Syndrome and Association with Physical Activity and Frailty Status in Spanish Older Adults with Decreased Functional Capacity: A Cross-Sectional Study 000117260 260__ $$c2022 000117260 5060_ $$aAccess copy available to the general public$$fUnrestricted 000117260 5203_ $$aMetabolic syndrome (MetS) is a cluster of medical conditions associated with several health disorders. MetS and frailty can be related to prolonged physical deconditioning. There is a need to know whether there is concordance between the different ways of diagnosing it and to know their prevalence in Spanish older adults. Thus, the aims of this study were to describe the prevalence of MetS; to analyse the concordance between different definitions to diagnose MetS; and to study the associations between MetS, frailty status, and physical activity (PA) in older adults with decreased functional capacity. This report is a cross-sectional study involving 110 Spanish older adults of ages ≥65 years with decreased functional capacity. Clinical criteria to diagnose MetS was defined by different expert groups. Anthropometric measurements, blood biochemical analysis, frailty status, functional capacity, and PA were assessed. The Kappa statistic was used to determine the agreement between the five MetS definitions used. Student’s t-test and the Pearson chi-square test were used to examine differences between sex, frailty, and PA groups. The sex-adjusted prevalence of MetS assessed by the National Cholesterol Education Program—Third Adult Treatment Panel was 39.4% in men and 32.5% in women. The International Diabetes Federation and the Harmonized definitions had the best agreement (k = 1.000). The highest odds ratios (ORs) of cardiometabolic risk factors to develop MetS were elevated triglycerides (37.5) and reduced high-density lipoprotein cholesterol (27.3). Central obesity and hypertension prevalence were significantly higher in the non-active group (70.7% and 26.8%, respectively), compared to the active group (50.0% and 7.7%, respectively). Moreover, the active group (OR = 0.85, 95% CI = 0.35, 2.04) and active women group (OR = 0.77, 95% CI = 0.27, 2.20) appeared to show a lower risk of developing this syndrome. MetS is highly prevalent in this sample and changes according to the definition used. It seems that sex and frailty do not influence the development of MetS. However, PA appears to decrease central obesity, hypertension, and the risk of developing MetS. 000117260 536__ $$9info:eu-repo/grantAgreement/ES/DGA-IIU/1-2020$$9info:eu-repo/grantAgreement/ES/FEDER/CB16-10-00477$$9info:eu-repo/grantAgreement/ES/MCIU/FPU18-05787$$9info:eu-repo/grantAgreement/ES/MINECO/BES-2017-081402$$9info:eu-repo/grantAgreement/ES/MINECO/DEP2016-78309-R$$9info:eu-repo/grantAgreement/ES/UZ/UZCUD2016-BIO-01$$9info:eu-repo/grantAgreement/ES/UZ/UZCUD2017-BIO-01 000117260 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000117260 590__ $$a5.9$$b2022 000117260 592__ $$a1.291$$b2022 000117260 591__ $$aNUTRITION & DIETETICS$$b17 / 87 = 0.195$$c2022$$dQ1$$eT1 000117260 593__ $$aNutrition and Dietetics$$c2022$$dQ1 000117260 593__ $$aFood Science$$c2022$$dQ1 000117260 594__ $$a9.0$$b2022 000117260 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000117260 700__ $$0(orcid)0000-0001-6523-5511$$aNavarrete-Villanueva, David$$uUniversidad de Zaragoza 000117260 700__ $$0(orcid)0000-0003-4789-9618$$aFernández-García, Ángel Iván$$uUniversidad de Zaragoza 000117260 700__ $$0(orcid)0000-0003-0330-5558$$aMoradell, Ana$$uUniversidad de Zaragoza 000117260 700__ $$aGesteiro, Eva 000117260 700__ $$0(orcid)0000-0002-4054-9132$$aPérez-Gómez, Jorge 000117260 700__ $$0(orcid)0000-0002-2854-6684$$aAra, Ignacio 000117260 700__ $$0(orcid)0000-0002-4303-4097$$aVicente-Rodríguez, Germán$$uUniversidad de Zaragoza 000117260 700__ $$0(orcid)0000-0002-7215-6931$$aCasajús, José Antonio$$uUniversidad de Zaragoza 000117260 700__ $$0(orcid)0000-0001-6492-2512$$aGómez-Cabello, Alba 000117260 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería 000117260 7102_ $$11006$$2245$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Educación Física y Depor. 000117260 773__ $$g14, 11 (2022), 2302 [19 pp.]$$pNutrients$$tNutrients$$x2072-6643 000117260 8564_ $$s553097$$uhttps://zaguan.unizar.es/record/117260/files/texto_completo.pdf$$yVersión publicada 000117260 8564_ $$s2923832$$uhttps://zaguan.unizar.es/record/117260/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000117260 909CO $$ooai:zaguan.unizar.es:117260$$particulos$$pdriver 000117260 951__ $$a2024-03-18-15:11:24 000117260 980__ $$aARTICLE