117387 20230519145555.0 doi 10.1371/journal.pone.0261313 sideral 126766 ART-2021-126766 eng Gómez-Soria I. Universidad de Zaragoza (orcid)0000-0002-0061-3312 Short-term memory, attention, and temporal orientation as predictors of the cognitive impairment in older adults: A cross-sectional observational study 2021 Access copy available to the general public Unrestricted Late-life cognitive decline ranges from the mildest cases of normal, age-related change to mild cognitive impairment to severe cases of dementia. Dementia is the largest global burden for the 21st century welfare and healthcare systems. The aim of this study was to analyze the neuropsychological constructs (temporal orientation (TO), spatial orientation (SO), fixation memory (FM), attention (A), calculation (C), short-term memory (STM), language (L), and praxis (P)), semantic fluency, level of functionality, and mood that reveal the greatest deficit in the different stages ranging from normal cognition (NC) to cognitive impairment in older adults in a primary healthcare setting. The study included 337 participants (102 men, 235 women), having a mean age of 74 ± 6 years. According to their scores on the Spanish version of the Mini-Mental State Examination (MEC-35), subjects were divided into 4 groups: no deterioration (ND) (score 32-35), subtle cognitive impairment (SCI) (score 28- 31), level deterioration (LD) (score 24-27) and moderate deterioration (MD) (score 20-23). The ND group revealed significant differences in TO, STM, C, A, L, P, and S-T as compared to the other groups. The MD group (in all the neuropsychological constructs) and the ND and SCI groups showed significant differences on the Yesavage geriatric depression scale (GDS-15). All except the FM neuropsychological construct were part of the MEC-35 prediction model and all of the regression coefficients were significant for these variables in the model. Furthermore, the highest average percentage of relative deterioration occurs between LD and MD and the greatest deterioration is observed in the STM for all groups, including A and TO for the LD and MD groups. Based on our findings, community programs have been implemented that use cognitive stimulation to prevent cognitive decline and to maintain the neuropsychological constructs. © 2021 Gómez-Soria et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 3.752 2021 MULTIDISCIPLINARY SCIENCES 29 / 74 = 0.392 2021 Q2 T2 0.852 2021 Multidisciplinary 2021 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Ferreira C. Universidad de Zaragoza (orcid)0000-0002-3698-6719 Oliván Blázquez B. Universidad de Zaragoza (orcid)0000-0001-6565-9699 Magallón Botaya R.M. Universidad de Zaragoza (orcid)0000-0002-5494-6550 Calatayud E. Universidad de Zaragoza (orcid)0000-0002-4307-796X 2005 595 Universidad de Zaragoza Dpto. Matemática Aplicada Área Matemática Aplicada 4009 740 Universidad de Zaragoza Dpto. Psicología y Sociología Área Psicología Social 1007 610 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Medicina 1006 413 Universidad de Zaragoza Dpto. Fisiatría y Enfermería Área Fisioterapia 16, 12 (2021), e0261313 [18 pp] PLoS One PLoS ONE 1932-6203 676768 http://zaguan.unizar.es/record/117387/files/texto_completo.pdf Versión publicada 2431076 http://zaguan.unizar.es/record/117387/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:117387 articulos driver 2023-05-18-15:53:42 ARTICLE