000117432 001__ 117432
000117432 005__ 20240319080957.0
000117432 0247_ $$2doi$$a10.1002/aoc.6661
000117432 0248_ $$2sideral$$a128682
000117432 037__ $$aART-2022-128682
000117432 041__ $$aeng
000117432 100__ $$aLuengo, Andres
000117432 245__ $$aSynthesis and antiproliferative study of phosphorescent multimetallic Re(I)/Au(I) complexes containing fused imidazo[4, 5-f]-1, 10-phenanthroline core
000117432 260__ $$c2022
000117432 5060_ $$aAccess copy available to the general public$$fUnrestricted
000117432 5203_ $$aFive heterobimetallic Re-I/Au-I and a tri-metallic Re-I/Au-I/Re-I species following the formulas fac-ReCl (CO)(3)(NNCAuR)](0/+) and (fac-ReCl (CO)(3)(NNC)])(2)Au](+), where R is an iodide (1), phenylacetylene (2), dodecanethiol (3), 2, 3, 4, 6-tetra-O-acetyl-1-thio-beta-D-glucopyranose (4) and JohnPhos (5) and NNC is the fused imidazo4, 5-f]-1, 10-phenanthroline heterotopic ligand, were synthesised and fully characterised by a variety of spectroscopic and analytical techniques. The resultant complexes are luminescent in the orange region, revealing classical metal-to-ligand charge transfer ((MLCT)-M-3) ((Re (d pi) -> (NNC)(pi*)) emission in aerated DMSO solution. The red shifted emission observed on going from 3 to 4 suggests that the electronic properties of the gold ancillary ligand are implicated in the emissive properties. Antiproliferative activity in tumour cell lines, lung (A549) and cervix (HeLa) cells revealed that only complex 4 containing a 2, 3, 4, 6-tetra-O-acetyl-1-thio-beta-D-glucopyranose as gold ancillary ligand possesses certain cytotoxicity in both cell lines.
000117432 536__ $$9info:eu-repo/grantAgreement/ES/DGA-FSE/E07-20R$$9info:eu-repo/grantAgreement/ES/MCIU/PID2019-104379RB-C21$$9info:eu-repo/grantAgreement/ES/MCIU/RED2018-102471-T$$9info:eu-repo/grantAgreement/ES/MCIU/RTI2018-097836-J-I00$$9info:eu-repo/grantAgreement/ES/MCIU/RYC2018-025872
000117432 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttp://creativecommons.org/licenses/by-nc/3.0/es/
000117432 590__ $$a3.9$$b2022
000117432 592__ $$a0.518$$b2022
000117432 591__ $$aCHEMISTRY, INORGANIC & NUCLEAR$$b8 / 42 = 0.19$$c2022$$dQ1$$eT1
000117432 593__ $$aInorganic Chemistry$$c2022$$dQ2
000117432 591__ $$aCHEMISTRY, APPLIED$$b22 / 72 = 0.306$$c2022$$dQ2$$eT1
000117432 593__ $$aChemistry (miscellaneous)$$c2022$$dQ2
000117432 594__ $$a7.3$$b2022
000117432 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000117432 700__ $$0(orcid)0000-0002-2315-9079$$aMarzo, Isabel$$uUniversidad de Zaragoza
000117432 700__ $$0(orcid)0000-0002-1218-7218$$aFernandez-Moreira, Vanesa$$uUniversidad de Zaragoza
000117432 700__ $$0(orcid)0000-0003-0553-0695$$aGimeno, M. Concepcion
000117432 7102_ $$12010$$2760$$aUniversidad de Zaragoza$$bDpto. Química Inorgánica$$cÁrea Química Inorgánica
000117432 7102_ $$11002$$2050$$aUniversidad de Zaragoza$$bDpto. Bioq.Biolog.Mol. Celular$$cÁrea Biología Celular
000117432 773__ $$ge6661 (2022), [11 pp]$$pAppl. organomet. chem.$$tAPPLIED ORGANOMETALLIC CHEMISTRY$$x0268-2605
000117432 8564_ $$s2205483$$uhttps://zaguan.unizar.es/record/117432/files/texto_completo.pdf$$yVersión publicada
000117432 8564_ $$s2327776$$uhttps://zaguan.unizar.es/record/117432/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000117432 909CO $$ooai:zaguan.unizar.es:117432$$particulos$$pdriver
000117432 951__ $$a2024-03-18-13:45:07
000117432 980__ $$aARTICLE