117432 20240319080957.0 doi 10.1002/aoc.6661 sideral 128682 ART-2022-128682 eng Luengo, Andres Synthesis and antiproliferative study of phosphorescent multimetallic Re(I)/Au(I) complexes containing fused imidazo[4, 5-f]-1, 10-phenanthroline core 2022 Access copy available to the general public Unrestricted Five heterobimetallic Re-I/Au-I and a tri-metallic Re-I/Au-I/Re-I species following the formulas fac-ReCl (CO)(3)(NNCAuR)](0/+) and (fac-ReCl (CO)(3)(NNC)])(2)Au](+), where R is an iodide (1), phenylacetylene (2), dodecanethiol (3), 2, 3, 4, 6-tetra-O-acetyl-1-thio-beta-D-glucopyranose (4) and JohnPhos (5) and NNC is the fused imidazo4, 5-f]-1, 10-phenanthroline heterotopic ligand, were synthesised and fully characterised by a variety of spectroscopic and analytical techniques. The resultant complexes are luminescent in the orange region, revealing classical metal-to-ligand charge transfer ((MLCT)-M-3) ((Re (d pi) -> (NNC)(pi*)) emission in aerated DMSO solution. The red shifted emission observed on going from 3 to 4 suggests that the electronic properties of the gold ancillary ligand are implicated in the emissive properties. Antiproliferative activity in tumour cell lines, lung (A549) and cervix (HeLa) cells revealed that only complex 4 containing a 2, 3, 4, 6-tetra-O-acetyl-1-thio-beta-D-glucopyranose as gold ancillary ligand possesses certain cytotoxicity in both cell lines. info:eu-repo/grantAgreement/ES/DGA-FSE/E07-20R info:eu-repo/grantAgreement/ES/MCIU/PID2019-104379RB-C21 info:eu-repo/grantAgreement/ES/MCIU/RED2018-102471-T info:eu-repo/grantAgreement/ES/MCIU/RTI2018-097836-J-I00 info:eu-repo/grantAgreement/ES/MCIU/RYC2018-025872 info:eu-repo/semantics/openAccess by-nc http://creativecommons.org/licenses/by-nc/3.0/es/ 3.9 2022 CHEMISTRY, INORGANIC & NUCLEAR 8 / 42 = 0.19 2022 Q1 T1 CHEMISTRY, APPLIED 22 / 72 = 0.306 2022 Q2 T1 0.518 2022 Inorganic Chemistry 2022 Q2 Chemistry (miscellaneous) 2022 Q2 7.3 2022 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Marzo, Isabel Universidad de Zaragoza (orcid)0000-0002-2315-9079 Fernandez-Moreira, Vanesa Universidad de Zaragoza (orcid)0000-0002-1218-7218 Gimeno, M. Concepcion (orcid)0000-0003-0553-0695 2010 760 Universidad de Zaragoza Dpto. Química Inorgánica Área Química Inorgánica 1002 050 Universidad de Zaragoza Dpto. Bioq.Biolog.Mol. Celular Área Biología Celular e6661 (2022), [11 pp] Appl. organomet. chem. APPLIED ORGANOMETALLIC CHEMISTRY 0268-2605 2205483 http://zaguan.unizar.es/record/117432/files/texto_completo.pdf Versión publicada 2327776 http://zaguan.unizar.es/record/117432/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:117432 articulos driver 2024-03-18-13:45:07 ARTICLE