117437 20240319080957.0 doi 10.1002/anie.202117006 sideral 128688 ART-2022-128688 eng Galiana-Cameo, Maria Universidad de Zaragoza (orcid)0000-0002-2043-4864 Rhodium-NHC-Catalyzed gem-Specific O-Selective Hydropyridonation of Terminal Alkynes 2022 Access copy available to the general public Unrestricted The dinuclear complex Rh(mu-Cl)(eta(2)-coe)(IPr)](2) is an efficient catalyst for the O-selective Markovnikov-type addition of 2-pyridones to terminal alkynes. DFT calculations support a hydride-free pathway entailing intramolecular oxidative protonation of a pi-alkyne by a kappa N-1-hydroxypyridine ligand. Subsequent O-nucleophilic attack on a metallacyclopropene species affords an O-alkenyl-2-oxypyridine chelate rhodium intermediate as the catalyst resting state. The release of the alkenyl ether is calculated as the rate-determining step. info:eu-repo/grantAgreement/ES/DGA-FSE/E42-20R info:eu-repo/grantAgreement/ES/MICINN-FEDER/PID2019-103965GB-I00 info:eu-repo/grantAgreement/ES/MICINN/PGC2018-099383-B-I00 info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 16.6 2022 CHEMISTRY, MULTIDISCIPLINARY 13 / 178 = 0.073 2022 Q1 T1 5.573 2022 Chemistry (miscellaneous) 2022 Q1 Catalysis 2022 Q1 26.3 2022 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Romeo, Raul Urriolabeitia, Asier Universidad de Zaragoza (orcid)0000-0001-9352-6922 Passarelli, Vincenzo (orcid)0000-0002-1735-6439 Perez-Torrente, Jesus J. Universidad de Zaragoza (orcid)0000-0002-3327-0918 Polo, Victor Universidad de Zaragoza (orcid)0000-0001-5823-7965 Castarlenas, Ricardo (orcid)0000-0003-4460-8678 2010 760 Universidad de Zaragoza Dpto. Química Inorgánica Área Química Inorgánica 2012 755 Universidad de Zaragoza Dpto. Química Física Área Química Física 61, 20 (2022), e2021170 [5 pp] Angew. Chem. (Int. ed.) ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 1433-7851 4198610 http://zaguan.unizar.es/record/117437/files/texto_completo.pdf Versión publicada 2842126 http://zaguan.unizar.es/record/117437/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:117437 articulos driver 2024-03-18-13:45:57 ARTICLE