117601 20220711110508.0 doi 10.1117/1.JBO.23.3.035003 sideral 105309 ART-2018-105309 eng Remón, L. Universidad de Zaragoza (orcid)0000-0002-3979-4528 Influence of material and haptic design on the mechanical stability of intraocular lenses by means of finite-element modeling 2018 Intraocular lenses (IOLs) are used in the cataract treatment for surgical replacement of the opacified crystalline lens. Before being implanted they have to pass the strict quality control to guarantee a good biomechanical stability inside the capsular bag, avoiding the rotation, and to provide a good optical quality. The goal of this study was to investigate the influence of the material and haptic design on the behavior of the IOLs under dynamic compression condition. For this purpose, the strain-stress characteristics of the hydrophobic and hydrophilic materials were estimated experimentally. Next, these data were used as the input for a finite-element model (FEM) to analyze the stability of different IOL haptic designs, according to the procedure described by the ISO standards. Finally, the simulations of the effect of IOL tilt and decentration on the optical performance were performed in an eye model using a ray-tracing software. The results suggest the major importance of the haptic design rather than the material on the postoperative behavior of an IOL. FEM appears to be a powerful tool for numerical studies of the biomechanical properties of IOLs and it allows one to help in the design phase to the manufacturers. Access copy available to the general public Unrestricted info:eu-repo/grantAgreement/ES/MINECO/DPI2014-54981-R info:eu-repo/grantAgreement/ES/MINECO-FEDER/DPI2017-84047-R info:eu-repo/grantAgreement/ES/UZ-IBERCAJA-CAI/CM02-7 info:eu-repo/grantAgreement/ES/UZ/ICTS NANBIOSIS-U13 Unit-CIBER-BBN info:eu-repo/semantics/openAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 2.555 2018 BIOCHEMICAL RESEARCH METHODS 34 / 78 = 0.436 2018 Q2 T2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING 52 / 129 = 0.403 2018 Q2 T2 OPTICS 37 / 95 = 0.389 2018 Q2 T2 0.868 2018 Atomic and Molecular Physics, and Optics 2018 Q1 Electronic, Optical and Magnetic Materials 2018 Q1 Biomedical Engineering 2018 Q1 Biomaterials 2018 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Siedlecki, D. Cabeza-Gil, I. (orcid)0000-0001-8219-2365 Calvo, B. Universidad de Zaragoza (orcid)0000-0001-9713-1813 2002 647 Universidad de Zaragoza Dpto. Física Aplicada Área Óptica 5004 605 Universidad de Zaragoza Dpto. Ingeniería Mecánica Área Mec.Med.Cont. y Teor.Est. 23, 3 (2018), 035003 [10 pp.] J. biomed. opt. JOURNAL OF BIOMEDICAL OPTICS 1083-3668 3235998 http://zaguan.unizar.es/record/117601/files/texto_completo.pdf Versión publicada 1191187 http://zaguan.unizar.es/record/117601/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:117601 articulos driver 2022-07-11-08:47:12 ARTICLE