117623 20240319081006.0 doi 10.1016/j.neulet.2022.136619 sideral 129169 ART-2022-129169 eng Ródenas-González, F. Effects of ketosis on cocaine-induced reinstatement in male mice; 2022 Access copy available to the general public Unrestricted In recent years, the benefits of the ketogenic diet (KD) on different psychiatric disorders have been gaining attention, but the substance abuse field is still unexplored. Some studies have reported that palatable food can modulate the rewarding effects of cocaine, but the negative metabolic consequences rule out the recommendation of using it as a complementary treatment. Thus, the main aim of this study was to evaluate the effects of the KD on cocaine conditioned place preference (CPP) during acquisition, extinction, and reinstatement. 41 OF1 male mice were employed to assess the effects of the KD on a 10 mg/kg cocaine-induced CPP. Animals were divided into three groups: SD, KD, and KD after the Post-Conditioning test. The results revealed that, while access to the KD did not block CPP acquisition, it did significantly reduce the number of sessions required to extinguish the drug-associated memories and it blocked the priming-induced reinstatement. © 2022 The Author(s) info:eu-repo/grantAgreement/ES/MICINN/PID2020-112672RB-100 info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 2.5 2022 NEUROSCIENCES 198 / 272 = 0.728 2022 Q3 T3 0.802 2022 Neuroscience (miscellaneous) 2022 Q2 5.9 2022 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Blanco-Gandía, M. C. Universidad de Zaragoza (orcid)0000-0001-5990-1266 Miñarro, J. Rodríguez-Arias, M. 4009 735 Universidad de Zaragoza Dpto. Psicología y Sociología Área Psicolog.Evolut.Educac 778 (2022), 136619 [6 pp] Neurosci. lett. NEUROSCIENCE LETTERS 0304-3940 631050 http://zaguan.unizar.es/record/117623/files/texto_completo.pdf Versión publicada 2739619 http://zaguan.unizar.es/record/117623/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:117623 articulos driver 2024-03-18-14:42:09 ARTICLE