000117669 001__ 117669
000117669 005__ 20240319081027.0
000117669 0247_ $$2doi$$a10.5498/wjp.v12.i1.24
000117669 0248_ $$2sideral$$a128852
000117669 037__ $$aART-2022-128852
000117669 041__ $$aeng
000117669 100__ $$aCalpe-Lopez, Claudia
000117669 245__ $$aResilience to the effects of social stress on vulnerability to developing drug addiction
000117669 260__ $$c2022
000117669 5060_ $$aAccess copy available to the general public$$fUnrestricted
000117669 5203_ $$aWe review the still scarce but growing literature on resilience to the effects of social stress on the rewarding properties of drugs of abuse. We define the concept of resilience and how it is applied to the field of drug addiction research. We also describe the internal and external protective factors associated with resilience, such as individual behavioral traits and social support. We then explain the physiological response to stress and how it is modulated by resilience factors. In the subsequent section, we describe the animal models commonly used in the study of resilience to social stress, and we focus on the effects of chronic social defeat (SD), a kind of stress induced by repeated experience of defeat in an agonistic encounter, on different animal behaviors (depression- and anxiety-like behavior, cognitive impairment and addiction-like symptoms). We then summarize the current knowledge on the neurobiological substrates of resilience derived from studies of resilience to the effects of chronic SD stress on depression- and anxiety-related behaviors in rodents. Finally, we focus on the limited studies carried out to explore resilience to the effects of SD stress on the rewarding properties of drugs of abuse, describing the current state of knowledge and suggesting future research directions.
000117669 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttp://creativecommons.org/licenses/by-nc/3.0/es/
000117669 590__ $$a3.1$$b2022
000117669 591__ $$aPSYCHIATRY$$b91 / 154 = 0.591$$c2022$$dQ3$$eT2
000117669 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000117669 700__ $$aMartinez-Caballero, Maria A.
000117669 700__ $$aGarcia-Pardo, Maria P.$$uUniversidad de Zaragoza
000117669 700__ $$aAguilar, Maria A.
000117669 7102_ $$14009$$2735$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Psicolog.Evolut.Educac
000117669 773__ $$g12, 1 (2022), 24-58$$pWorld j. psychiatry$$tWORLD JOURNAL OF PSYCHIATRY$$x2220-3206
000117669 8564_ $$s1327092$$uhttps://zaguan.unizar.es/record/117669/files/texto_completo.pdf$$yVersión publicada
000117669 8564_ $$s1894635$$uhttps://zaguan.unizar.es/record/117669/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000117669 909CO $$ooai:zaguan.unizar.es:117669$$particulos$$pdriver
000117669 951__ $$a2024-03-18-16:48:39
000117669 980__ $$aARTICLE