117961 20230519145602.0 doi 10.31083/j.ejgo4204099 sideral 128047 ART-2021-128047 eng Baquedano Mainar, Laura Universidad de Zaragoza Clinical and demographic factors in endometrial and ovary carcinoma: Synchronous carcinoma vs stage IIIA endometrial carcinoma 2021 Access copy available to the general public Unrestricted Objective: To compare pre-surgical demographic and clinical factors and preoperative serum tumor marker values of patients with endometrial and ovarian synchronous carcinoma with those diagnosed with endometrial carcinoma with metastatic ovarian involvement (FIGO stage IIIA). Methods: A retrospective observational study including patients with endometrial and ovarian malignant tumors that were treated at Miguel Servet University Hospital, Zaragoza, Spain, since January 2000 to June 2020. All pathologic specimens were reviewed by two pathologists specialized in gynecological oncology. Results: Overall, 51 patients were included. 24 cases of them, were endometrial and ovarian synchronous primary carcinomas and the remaining 27 cases were endometrial tumors with adnexa. Parity, personal and family oncological history, arterial hypertension, diabetes, dyslipidemia, obesity and the prior use of hormone replacement therapy did not show significant differences between both groups. Age (p = 0.002), menopausal status (p = 0.029), abnormal uterine bleeding (p = 0.001), Ca 12.5 preoperative serum level (p = 0.038) and Ca 19.9 preoperative serum level (0.028) were factors with significant differences between both groups. In multivariate analysis, only abnormal uterine bleeding and Ca 19.9 values were independents factors. Conclusions: The presence of abnormal uterine bleeding and Ca 19.9 preoperative serum level could guide the clinician in the preoperative differential diagnosis between endometrial cancer with ovarian involvement and endometrial and ovarian synchronous carcinoma. © 2021 The Author(s). info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 0.255 2021 ONCOLOGY 243 / 245 = 0.992 2021 Q4 T3 OBSTETRICS & GYNECOLOGY 83 / 85 = 0.976 2021 Q4 T3 0.0 2021 Oncology 2021 Obstetrics and Gynecology 2021 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Navarro Sierra, Javier Alvárez Sarrado, Leticia (orcid)0000-0001-8957-2352 José Gutiérrez, Yasmina Lamarca Ballestero, Marta Rubio Cuesta, Patricia Ruiz Peña, Ana C. Espiau Romera, Andrea Universidad de Zaragoza 1013 645 Universidad de Zaragoza Dpto. Cirugía Área Obstetricia y Ginecología 42, 4 (2021), 643-648 Eur. j. gynaecol. oncol. EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY 0392-2936 116183 http://zaguan.unizar.es/record/117961/files/texto_completo.pdf Versión publicada 2929099 http://zaguan.unizar.es/record/117961/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:117961 articulos driver 2023-05-18-16:00:48 ARTICLE