000117965 001__ 117965
000117965 005__ 20230519145609.0
000117965 0247_ $$2doi$$a10.1016/j.clnu.2021.04.049
000117965 0248_ $$2sideral$$a127261
000117965 037__ $$aART-2021-127261
000117965 041__ $$aeng
000117965 100__ $$aMuñoz-Cabrejas, A.
000117965 245__ $$aHigh-quality intake of carbohydrates is associated with lower prevalence of subclinical atherosclerosis in femoral arteries: The AWHS study
000117965 260__ $$c2021
000117965 5060_ $$aAccess copy available to the general public$$fUnrestricted
000117965 5203_ $$aBackground and aims: High-quality of the carbohydrates consumed, apart from their total amount, appear to protect from cardiovascular disease (CVD). However, the relationship between the quality of carbohydrates and the early appearance of atherosclerosis has not yet been described. Our objective was to estimate the association between the quality of dietary carbohydrates and subclinical atherosclerosis in femoral and carotid arteries. Methods: Cross-sectional study of femoral and carotid atherosclerosis assessed using ultrasounds of 2074 middle-aged males, 50.9 (SD 3.9) years old, with no previous CVD, and pertaining to the Aragon Workers’ Health Study (AWHS) cohort. Food frequency questionnaires were used to calculate a carbohydrate quality index (CQI) defined as: consumption of dietary fiber, a lower glycemic index, the ratio of whole grains/total grains, and the ratio of solid carbohydrates/total carbohydrates. The presence of plaques across four CQI intervals was studied using adjusted logistic regression models. Results: The CQI showed a direct inverse association with subclinical atherosclerosis in femoral territories. Participants with a higher consumption of high-quality carbohydrates (13–15 points) were less likely to have femoral plaques when compared with participants in the lowest index interval (4–6 points) (OR = 0.59; 95% CI = 0.39, 0.89; p = 0.005). No association was found between the CQI and the presence of subclinical atherosclerosis in carotid territories. A lower consumption of high-quality carbohydrates tended to be associated with a greater atherosclerosis extension, considered as the odds for having more affected territories (p = 0.011). Conclusions: Among middle-aged males, a high-quality intake of carbohydrates is associated with a lower prevalence of femoral artery subclinical atherosclerosis when compared with a lower consumption. Thus, indicating an early relationship between the quality of carbohydrates and the development of CVD. © 2021 The Author(s)
000117965 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000117965 594__ $$a9.9$$b2021
000117965 590__ $$a7.643$$b2021
000117965 592__ $$a1.553$$b2021
000117965 591__ $$aNUTRITION & DIETETICS$$b13 / 90 = 0.144$$c2021$$dQ1$$eT1
000117965 593__ $$aNutrition and Dietetics$$c2021$$dQ1
000117965 593__ $$aCritical Care and Intensive Care Medicine$$c2021$$dQ1
000117965 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000117965 700__ $$0(orcid)0000-0003-3963-0846$$aLaclaustra, M.$$uUniversidad de Zaragoza
000117965 700__ $$aGuallar-Castillón, P.
000117965 700__ $$0(orcid)0000-0002-9887-2629$$aCasasnovas, J.A.$$uUniversidad de Zaragoza
000117965 700__ $$0(orcid)0000-0001-9142-0737$$aJarauta, E.$$uUniversidad de Zaragoza
000117965 700__ $$aSandoval-Insausti, H.
000117965 700__ $$aDonat-Vargas, C.
000117965 700__ $$0(orcid)0000-0003-0604-5042$$aMoreno-Franco, B.$$uUniversidad de Zaragoza
000117965 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000117965 7102_ $$11011$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Medic.Prevent.Salud Públ.
000117965 773__ $$g40, 6 (2021), 3883-3889$$pClin. nutr.$$tClinical Nutrition$$x0261-5614
000117965 8564_ $$s353238$$uhttps://zaguan.unizar.es/record/117965/files/texto_completo.pdf$$yVersión publicada
000117965 8564_ $$s2429111$$uhttps://zaguan.unizar.es/record/117965/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000117965 909CO $$ooai:zaguan.unizar.es:117965$$particulos$$pdriver
000117965 951__ $$a2023-05-18-16:07:12
000117965 980__ $$aARTICLE