000118042 001__ 118042 000118042 005__ 20240319081017.0 000118042 0247_ $$2doi$$a10.1080/19336918.2022.2055520 000118042 0248_ $$2sideral$$a128574 000118042 037__ $$aART-2022-128574 000118042 041__ $$aeng 000118042 100__ $$0(orcid)0000-0003-3852-0987$$aMerino Casallo, Francisco$$uUniversidad de Zaragoza 000118042 245__ $$aUnravelling cell migration: defining movement from the cell surface 000118042 260__ $$c2022 000118042 5060_ $$aAccess copy available to the general public$$fUnrestricted 000118042 5203_ $$aCell motility is essential for life and development. Unfortunately, cell migration is also linked to several pathological processes, such as cancer metastasis. Cells’ ability to migrate relies on many actors. Cells change their migratory strategy based on their phenotype and the properties of the surrounding microenvironment. Cell migration is, therefore, an extremely complex phenomenon. Researchers have investigated cell motility for more than a century. Recent discoveries have uncovered some of the mysteries associated with the mechanisms involved in cell migration, such as intracellular signaling and cell mechanics. These findings involve different players, including transmembrane receptors, adhesive complexes, cytoskeletal components , the nucleus, and the extracellular matrix. This review aims to give a global overview of our current understanding of cell migration. 000118042 536__ $$9info:eu-repo/grantAgreement/EC/H2020/826494/EU/PRedictive In-silico Multiscale Analytics to support cancer personalized diaGnosis and prognosis, Empowered by imaging biomarkers/PRIMAGE$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 826494-PRIMAGE$$9info:eu-repo/grantAgreement/ES/MICINN/RTI2018-094494-B-C21$$9info:eu-repo/grantAgreement/ES/MINECO/BES-2016-076291 000118042 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000118042 590__ $$a3.2$$b2022 000118042 592__ $$a0.746$$b2022 000118042 591__ $$aCELL BIOLOGY$$b127 / 191 = 0.665$$c2022$$dQ3$$eT3 000118042 593__ $$aCellular and Molecular Neuroscience$$c2022$$dQ3 000118042 593__ $$aCell Biology$$c2022$$dQ3 000118042 594__ $$a6.7$$b2022 000118042 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000118042 700__ $$0(orcid)0000-0002-1878-8997$$aGomez Benito, Maria Jose$$uUniversidad de Zaragoza 000118042 700__ $$0(orcid)0000-0001-8324-5596$$aHervas Raluy, Silvia$$uUniversidad de Zaragoza 000118042 700__ $$0(orcid)0000-0002-9864-7683$$aGarcia-Aznar, Jose Manuel$$uUniversidad de Zaragoza 000118042 7102_ $$15004$$2605$$aUniversidad de Zaragoza$$bDpto. Ingeniería Mecánica$$cÁrea Mec.Med.Cont. y Teor.Est. 000118042 773__ $$g16, 1 (2022), 25-64$$pCell adh. migr.$$tCell adhesion & migration$$x1933-6918 000118042 8564_ $$s4421680$$uhttps://zaguan.unizar.es/record/118042/files/texto_completo.pdf$$yVersión publicada 000118042 8564_ $$s991006$$uhttps://zaguan.unizar.es/record/118042/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000118042 909CO $$ooai:zaguan.unizar.es:118042$$particulos$$pdriver 000118042 951__ $$a2024-03-18-15:47:42 000118042 980__ $$aARTICLE