118042 20240319081017.0 doi 10.1080/19336918.2022.2055520 sideral 128574 ART-2022-128574 eng Merino Casallo, Francisco Universidad de Zaragoza (orcid)0000-0003-3852-0987 Unravelling cell migration: defining movement from the cell surface 2022 Access copy available to the general public Unrestricted Cell motility is essential for life and development. Unfortunately, cell migration is also linked to several pathological processes, such as cancer metastasis. Cells’ ability to migrate relies on many actors. Cells change their migratory strategy based on their phenotype and the properties of the surrounding microenvironment. Cell migration is, therefore, an extremely complex phenomenon. Researchers have investigated cell motility for more than a century. Recent discoveries have uncovered some of the mysteries associated with the mechanisms involved in cell migration, such as intracellular signaling and cell mechanics. These findings involve different players, including transmembrane receptors, adhesive complexes, cytoskeletal components , the nucleus, and the extracellular matrix. This review aims to give a global overview of our current understanding of cell migration. info:eu-repo/grantAgreement/EC/H2020/826494/EU/PRedictive In-silico Multiscale Analytics to support cancer personalized diaGnosis and prognosis, Empowered by imaging biomarkers/PRIMAGE This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 826494-PRIMAGE info:eu-repo/grantAgreement/ES/MICINN/RTI2018-094494-B-C21 info:eu-repo/grantAgreement/ES/MINECO/BES-2016-076291 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 3.2 2022 CELL BIOLOGY 127 / 191 = 0.665 2022 Q3 T3 0.746 2022 Cellular and Molecular Neuroscience 2022 Q3 Cell Biology 2022 Q3 6.7 2022 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Gomez Benito, Maria Jose Universidad de Zaragoza (orcid)0000-0002-1878-8997 Hervas Raluy, Silvia Universidad de Zaragoza (orcid)0000-0001-8324-5596 Garcia-Aznar, Jose Manuel Universidad de Zaragoza (orcid)0000-0002-9864-7683 5004 605 Universidad de Zaragoza Dpto. Ingeniería Mecánica Área Mec.Med.Cont. y Teor.Est. 16, 1 (2022), 25-64 Cell adh. migr. Cell adhesion & migration 1933-6918 4421680 http://zaguan.unizar.es/record/118042/files/texto_completo.pdf Versión publicada 991006 http://zaguan.unizar.es/record/118042/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:118042 articulos driver 2024-03-18-15:47:42 ARTICLE