000118079 001__ 118079
000118079 005__ 20240319080955.0
000118079 0247_ $$2doi$$a10.1016/j.foodcont.2022.109033
000118079 0248_ $$2sideral$$a128822
000118079 037__ $$aART-2022-128822
000118079 041__ $$aeng
000118079 100__ $$0(orcid)0000-0003-3850-9833$$aSerrano, M.J.
000118079 245__ $$aAntimicrobial residue assessment in 5, 357 commercialized meat samples from the Spain-France cross-border area: A new approach for effective monitoring
000118079 260__ $$c2022
000118079 5060_ $$aAccess copy available to the general public$$fUnrestricted
000118079 5203_ $$aAlthough antimicrobials are valuable allies in animal production, their extended use has led to unexpected threats associated with the emergence and propagation of antimicrobial resistance. Moreover, when withdrawal periods in food-producing animals are not observed, antimicrobial residues can access the food chain, causing direct toxicity, allergies, and/or intestinal microbiota dysbiosis in consumers. Given that Spain and France are the largest meat producers in the EU and also count among the top consumers of meat, our study''s aim was to investigate the presence of antimicrobials in commercialized meat purchased in the Spain-France cross-border area (POCTEFA region). 5, 357 meat samples were collected from different animal species and a variety of different retailer types in Spain (Zaragoza, Bilbao, and Logroño) as well as in France (Toulouse and Perpignan). Meat samples were analysed by a screening method (Explorer®+QuinoScan®), yielding 194 positive samples, which were further evaluated by UPLC-QTOF (Ultra Performance Liquid Chromatography-Quadrupole Time of Flight) for confirmation. Chromatographic analyses found antimicrobial residues in 30 samples, although only 5 of them (0.093% of initial samples) were non-compliant according to the current legislation. Further studies suggested that this mismatch between screening and confirmatory analyses might be due to the presence of biologically active metabolites derived from degradation of antimicrobials that were not identified by the targeted UPLC-QTOF method, but which might play a decisive role in the inhibition of the biological Explorer® test. Although chromatographic techniques detect the marker compounds determined by European and national regulations, and although they are the methods selected for official control of antimicrobials in food, certain unknown metabolites might escape their monitoring. This thus suggests that biological tests are the most adequate ones in terms of ideal consumer health protection.
000118079 536__ $$9info:eu-repo/grantAgreement/EC/H2020/801586/EU/International Doctoral Programme for Talent Attraction to the Campus of International Excellence of the Ebro Valley/IberusTalent$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 801586-IberusTalent$$9info:eu-repo/grantAgreement/EUR/INTERREG-V-A-POCTEFA/TESTACOS-EFA152/16$$9info:eu-repo/grantAgreement/EUR/INTERREG-V-A-POCTEFA-2014-2020
000118079 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000118079 590__ $$a6.0$$b2022
000118079 592__ $$a1.057$$b2022
000118079 591__ $$aFOOD SCIENCE & TECHNOLOGY$$b24 / 142 = 0.169$$c2022$$dQ1$$eT1
000118079 593__ $$aFood Science$$c2022$$dQ1
000118079 593__ $$aBiotechnology$$c2022$$dQ1
000118079 594__ $$a10.6$$b2022
000118079 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000118079 700__ $$aElorduy, J.
000118079 700__ $$aZabaleta, I.
000118079 700__ $$aIstamboulie, G.
000118079 700__ $$aGonzález-Fandos, E.
000118079 700__ $$aBousquet-Mélou, A.
000118079 700__ $$aMata, L.
000118079 700__ $$aAymard, C.
000118079 700__ $$aMartínez-Laorden, A.
000118079 700__ $$aDa Silva-Guedes, J.
000118079 700__ $$aLacroix, M.
000118079 700__ $$0(orcid)0000-0002-7629-8101$$aGarcía-Gonzalo, D.$$uUniversidad de Zaragoza
000118079 700__ $$0(orcid)0000-0002-1902-0648$$aCondón, S.$$uUniversidad de Zaragoza
000118079 700__ $$aAbilleira, E.
000118079 700__ $$0(orcid)0000-0002-0238-6328$$aPagán, R.$$uUniversidad de Zaragoza
000118079 7102_ $$12008$$2780$$aUniversidad de Zaragoza$$bDpto. Produc.Animal Cienc.Ali.$$cÁrea Tecnología de Alimentos
000118079 773__ $$g138 (2022), 109033 [11 pp.]$$pFood control$$tFood Control$$x0956-7135
000118079 8564_ $$s1183856$$uhttps://zaguan.unizar.es/record/118079/files/texto_completo.pdf$$yVersión publicada
000118079 8564_ $$s2282812$$uhttps://zaguan.unizar.es/record/118079/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000118079 909CO $$ooai:zaguan.unizar.es:118079$$particulos$$pdriver
000118079 951__ $$a2024-03-18-13:30:10
000118079 980__ $$aARTICLE