000118273 001__ 118273
000118273 005__ 20240319081017.0
000118273 0247_ $$2doi$$a10.1002/ejoc.202200093
000118273 0248_ $$2sideral$$a129545
000118273 037__ $$aART-2022-129545
000118273 041__ $$aeng
000118273 100__ $$aAscaso-Alegre, C.
000118273 245__ $$aConstruction of Chemoenzymatic Linear Cascades for the Synthesis of Chiral Compounds
000118273 260__ $$c2022
000118273 5060_ $$aAccess copy available to the general public$$fUnrestricted
000118273 5203_ $$aInspired by nature, synthetic chemists try to mimic the efficient metabolic networks in living organisms to build complex molecules by combining different types of catalysts in the same reaction vessel. These multistep cascade processes provide many advantages to synthetic procedures, resulting in higher productivities with lower waste generation and cost. However, combining different chemo- and biocatalysts can be challenging as reaction conditions might differ greatly. As a highly multidisciplinary field that benefits from advances in chemical catalysis, molecular biology and reaction engineering, this area of study is rapidly progressing. In this Review, we highlight recent trends and advances in the construction of multistep chemoenzymatic one-pot cascades to access chiral compounds as well as the different strategies to solve current challenges in the field.
000118273 536__ $$9info:eu-repo/grantAgreement/ES/DGA/E07-20R$$9info:eu-repo/grantAgreement/ES/MICINN/PID2020-113351RA-I00/AEI/10.13039/501100011033
000118273 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttp://creativecommons.org/licenses/by-nc/3.0/es/
000118273 590__ $$a2.8$$b2022
000118273 592__ $$a0.682$$b2022
000118273 591__ $$aCHEMISTRY, ORGANIC$$b16 / 52 = 0.308$$c2022$$dQ2$$eT1
000118273 593__ $$aPhysical and Theoretical Chemistry$$c2022$$dQ2
000118273 593__ $$aOrganic Chemistry$$c2022$$dQ2
000118273 594__ $$a5.5$$b2022
000118273 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000118273 700__ $$0(orcid)0000-0002-3364-1512$$aMangas-Sanchez, J.
000118273 773__ $$g2022, 22 (2022), e202200093 [9 pp.]$$pEUR J ORG CHEM$$tEuropean Journal of Organic Chemistry$$x1434-193X
000118273 8564_ $$s6905794$$uhttps://zaguan.unizar.es/record/118273/files/texto_completo.pdf$$yVersión publicada
000118273 8564_ $$s2925527$$uhttps://zaguan.unizar.es/record/118273/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000118273 909CO $$ooai:zaguan.unizar.es:118273$$particulos$$pdriver
000118273 951__ $$a2024-03-18-15:48:31
000118273 980__ $$aARTICLE