118280 20240319081018.0 doi 10.3390/ani12131620 sideral 129557 ART-2022-129557 eng Bernad-Roche, M. Universidad de Zaragoza (orcid)0000-0002-3017-3012 Salmonella Shedding in Slaughter Pigs and the Use of Esterified Formic Acid in the Drinking Water as a Potential Abattoir-Based Mitigation Measure 2022 Access copy available to the general public Unrestricted Pigs shedding Salmonella at slaughter are considered a source of carcass contamination and human infection. To assess this potential risk, the proportion of Salmonella shedders that arrive for slaughter was evaluated in a population of 1068 pigs from 24 farms. Shedding was present in 27.3% of the pigs, and the monophasic variant of Salmonella Typhimurium, an emerging zoonotic serotype, was the most prevalent (46.9%). Antimicrobial resistance (AMR) in Salmonella isolates was common, but few isolates showed AMR to antimicrobials of critical importance for humans such as third-generation cephalosporins (5%), colistin (0%), or carbapenems (0%). However, AMR to tigecycline was moderately high (15%). The efficacy of an esterified formic acid in the lairage drinking water (3 kg formic acid/1000 L) was also assessed as a potential abattoir-based strategy to reduce Salmonella shedding. It was able to reduce the proportion of shedders (60.7% in the control group (CG) vs. 44.3% in the treatment group (TG); p < 0.01). After considering clustering and confounding factors, the odds of shedding Salmonella in the CG were 2.75 (95% CI = 1.80–4.21) times higher than those of the TG, suggesting a potential efficacy of reduction in shedding as high as 63.6%. This strategy may contribute to mitigating the burden of abattoir environmental contamination. info:eu-repo/grantAgreement/ES/MICINN/RTI2018-093915-B-I00 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 3.0 2022 VETERINARY SCIENCES 13 / 144 = 0.09 2022 Q1 T1 AGRICULTURE, DAIRY & ANIMAL SCIENCE 12 / 62 = 0.194 2022 Q1 T1 0.684 2022 Veterinary (miscellaneous) 2022 Q1 Animal Science and Zoology 2022 Q1 4.2 2022 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Casanova-Higes, A. Universidad de Zaragoza (orcid)0000-0002-9340-0665 Marín-Alcalá, C.M. (orcid)0000-0002-1974-9025 Mainar-Jaime, R. Universidad de Zaragoza (orcid)0000-0001-5442-7702 1009 773 Universidad de Zaragoza Dpto. Patología Animal Área Sanidad Animal 12, 13 (2022), 1620 [16 pp.] Animals (Basel) Animals 2076-2615 467211 http://zaguan.unizar.es/record/118280/files/texto_completo.pdf Versión publicada 2724764 http://zaguan.unizar.es/record/118280/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:118280 articulos driver 2024-03-18-15:55:40 ARTICLE