000118641 001__ 118641 000118641 005__ 20240319080950.0 000118641 0247_ $$2doi$$a10.1007/s00264-021-05272-2 000118641 0248_ $$2sideral$$a126932 000118641 037__ $$aART-2022-126932 000118641 041__ $$aeng 000118641 100__ $$aJiménez-del-Barrio, S. 000118641 245__ $$aThe effectiveness of manual therapy on pain, physical function, and nerve conduction studies in carpal tunnel syndrome patients: a systematic review and meta-analysis 000118641 260__ $$c2022 000118641 5060_ $$aAccess copy available to the general public$$fUnrestricted 000118641 5203_ $$aAim of the study: Systematic review and meta-analysis to assess the effectiveness of manual therapy in improving carpal tunnel syndrome (CTS) symptoms, physical function, and nerve conduction studies. Method: MEDLINE, Web of Science, SCOPUS, Cochrane Library, TRIP database, and PEDro databases were searched from the inception to September 2021. PICO search strategy was used to identify randomized controlled trials applying manual therapy on patients with CTS. Eligible studies and data extraction were conducted independently by two reviewers. Methodology quality and risk of bias were assessed by PEDro scale. Outcomes assessed were pain intensity, physical function, and nerve conduction studies. Results: Eighty-one potential studies were identified and six studies involving 401 patients were finally included. Pain intensity immediately after treatment showed a pooled standard mean difference (SMD) of - 2.13 with 95% confidence interval (CI) (- 2.39, - 1.86). Physical function with Boston Carpal Tunnel Syndrome Questionnaire (BCTS-Q) showed a pooled SMD of - 1.67 with 95% CI (- 1.92, - 1.43) on symptoms severity, and a SMD of - 0.89 with 95% CI (- 1.08, - 0.70) on functional status. Nerve conduction studies showed a SMD of - 0.19 with 95% CI (- 0.40, - 0.02) on motor conduction and a SMD of - 1.15 with 95% CI (- 1.36, - 0.93) on sensory conduction. Conclusions: This study highlights the effectiveness of manual therapy techniques based on soft tissue and neurodynamic mobilizations, in isolation, on pain, physical function, and nerve conduction studies in patients with CTS. © 2021, The Author(s). 000118641 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000118641 590__ $$a2.7$$b2022 000118641 591__ $$aORTHOPEDICS$$b31 / 86 = 0.36$$c2022$$dQ2$$eT2 000118641 594__ $$a6.2$$b2022 000118641 592__ $$a0.988$$b2022 000118641 593__ $$aSurgery$$c2022$$dQ1 000118641 593__ $$aOrthopedics and Sports Medicine$$c2022$$dQ1 000118641 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000118641 700__ $$aCadellans-Arróniz, A. 000118641 700__ $$aCeballos-Laita, L. 000118641 700__ $$0(orcid)0000-0002-5161-7479$$aEstébanez-de-Miguel, E.$$uUniversidad de Zaragoza 000118641 700__ $$aLópez-de-Celis, C. 000118641 700__ $$0(orcid)0000-0002-0026-9224$$aBueno-Gracia , E.$$uUniversidad de Zaragoza 000118641 700__ $$aPérez-Bellmunt, A. 000118641 7102_ $$11006$$2413$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Fisioterapia 000118641 773__ $$g46 (2022), 301-312$$pInt. orthop.$$tINTERNATIONAL ORTHOPAEDICS$$x0341-2695 000118641 8564_ $$s1516783$$uhttps://zaguan.unizar.es/record/118641/files/texto_completo.pdf$$yVersión publicada 000118641 8564_ $$s1965463$$uhttps://zaguan.unizar.es/record/118641/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000118641 909CO $$ooai:zaguan.unizar.es:118641$$particulos$$pdriver 000118641 951__ $$a2024-03-18-12:59:48 000118641 980__ $$aARTICLE