000118745 001__ 118745
000118745 005__ 20231108202304.0
000118745 0247_ $$2doi$$a10.1002/vrc2.412
000118745 0248_ $$2sideral$$a129691
000118745 037__ $$aART-2022-129691
000118745 041__ $$aeng
000118745 100__ $$0(orcid)0000-0001-6209-4282$$aVillanueva Saz, S.$$uUniversidad de Zaragoza
000118745 245__ $$aSelective IgA deficiency and presumptive polyclonal spike in the beta fraction in a dog with leishmaniosis
000118745 260__ $$c2022
000118745 5060_ $$aAccess copy available to the general public$$fUnrestricted
000118745 5203_ $$aA 1-year-old, entire, crossbred, female dog examined for apathy, lethargy, unilateral nosebleed of 2-month duration and the presence of symmetrical ulcerative dermatitis (small ulcers covered by a haemorrhagic crust and surrounded by alopecia on the tip of the ear pinna). Laboratory alterations included anaemia and hyperglobulinemia with a presumptive polyclonal spike in the beta fraction. High antibody levels to Leishmania infantum were detected by enzyme-linked immunosorbent assay. An anti-Leishmania therapeutic protocol was established and a reduction of the anti-Leishmania antibodies was detected by an end point sera dilution enzyme-linked immunosorbent assay during the first weeks of therapeutic protocol, while C-reactive protein concentration was reduced during the period of time when meglumine antimoniate was administered. A good clinical response to the treatment was detected after initiating the anti-Leishmania treatment. Quantitative serology is useful in the short-term, because using a two-fold serial dilution technique correlates with the clinical response. © 2022 British Veterinary Association.
000118745 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000118745 592__ $$a0.176$$b2022
000118745 593__ $$aVeterinary (miscellaneous)$$c2022$$dQ3
000118745 594__ $$a0.4$$b2022
000118745 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000118745 700__ $$0(orcid)0000-0003-3043-147X$$aMartinez Lostao, L.$$uUniversidad de Zaragoza
000118745 700__ $$aYzuel, A.
000118745 700__ $$0(orcid)0000-0002-2557-4890$$aFernández, A.$$uUniversidad de Zaragoza
000118745 700__ $$0(orcid)0000-0003-2957-1379$$aVerde, M.$$uUniversidad de Zaragoza
000118745 7102_ $$11011$$2566$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Inmunología
000118745 7102_ $$11009$$2617$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Medicina y Cirugía Animal
000118745 773__ $$g10, 3 (2022), e412 [6 pp]$$pVet. rec. case rep.$$tVeterinary Record Case Reports$$x2052-6121
000118745 8564_ $$s335862$$uhttps://zaguan.unizar.es/record/118745/files/texto_completo.pdf$$yVersión publicada
000118745 8564_ $$s2979592$$uhttps://zaguan.unizar.es/record/118745/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000118745 909CO $$ooai:zaguan.unizar.es:118745$$particulos$$pdriver
000118745 951__ $$a2023-11-08-20:19:34
000118745 980__ $$aARTICLE