118747 20240319081025.0 doi 10.3390/jof8050547 sideral 129700 ART-2022-129700 eng Zhu, G.-Y Peel Diffusion and Antifungal Efficacy of Different Fungicides in Pear Fruit: Structure-Diffusion-Activity Relationships 2022 Access copy available to the general public Unrestricted Fungal pathogens can invade not only the fruit peel but also the outer part of the fruit mesocarp, limiting the efficacy of fungicides. In this study, the relationships between fungicide structure, diffusion capacity and in vivo efficacy were evaluated for the first time. The diffusion capacity from pear peel to mesocarp of 11 antifungal compounds, including p-aminobenzoic acid, carbendazim, difenoconazole, dipicolinic acid, flusilazole, gentamicin, kojic acid, prochloraz, quino-linic acid, thiophanate methyl and thiram was screened. The obtained results indicated that size and especially polarity were negatively correlated with the diffusion capacity. Although some antifungal compounds, such as prochloraz and carbendazim, were completely degraded after a few days in peel and mesocarp, other compounds, such as p-aminobenzoic acid and kojic acid, showed high stability. When applying the antifungal compounds at the EC50 concentrations, it was observed that the compounds with high diffusion capacity showed higher in vivo antifungal activity against Alternaria alternata than compounds with low diffusion capacity. In contrast, there was no relationship between stability and in vivo efficacy. Collectively, the obtained results indicated that the diffusion capacity plays an important role in the efficacy of fungicides for the control of pear fruit diseases. © 2022 by the authors. Licensee MDPI, Basel, Switzerland. info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 4.7 2022 MYCOLOGY 9 / 30 = 0.3 2022 Q2 T1 MICROBIOLOGY 45 / 135 = 0.333 2022 Q2 T2 0.871 2022 Ecology, Evolution, Behavior and Systematics 2022 Q1 Plant Science 2022 Q1 Microbiology (medical) 2022 Q2 4.9 2022 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Chen, Y. Wang, S.-Y Shi, X.-C Herrera-Balandrano, D.D. Polo, V. Universidad de Zaragoza (orcid)0000-0001-5823-7965 Laborda, P. 2012 755 Universidad de Zaragoza Dpto. Química Física Área Química Física 8, 5 (2022), 547 [15 pp.] J. Fungi Journal of Fungi 2309-608X 2315355 http://zaguan.unizar.es/record/118747/files/texto_completo.pdf Versión publicada 2783331 http://zaguan.unizar.es/record/118747/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:118747 articulos driver 2024-03-18-16:35:41 ARTICLE