000118750 001__ 118750
000118750 005__ 20241125101128.0
000118750 0247_ $$2doi$$a10.14336/AD.2022.0424
000118750 0248_ $$2sideral$$a130193
000118750 037__ $$aART-2023-130193
000118750 041__ $$aeng
000118750 100__ $$aNuñez-Cortes, Rodrigo
000118750 245__ $$aRisk factors for one-year mortality in hospitalized adults with severe covid-19 comment
000118750 260__ $$c2023
000118750 5060_ $$aAccess copy available to the general public$$fUnrestricted
000118750 5203_ $$aAs the body's immunity declines with age, elderly-hospitalized patients due to COVID-19 might be at higher mortality risk. Therefore, the aim of this prospective study was to examine the possible risk factors (demographic, social or comorbidities) most associated with mortality one-year after diagnosis of COVID-19. Routine data were collected from a cohort of hospitalized adults with severe COVID-19. The primary endpoint was mortality at one-year after diagnosis of COVID-19. We used a Cox proportional hazard model to estimate the hazard ratios (HRs) for both all-cause and specific cardiorespiratory mortality. A fully adjusted model included sex, socioeconomic status, institutionalization status, disability, smoking habit, and comorbidities as confounders. A total of 368 severe cases hospitalized on average 67.3 +/- 15.9 years old were included. Participants aged >= 71 years had significantly higher HRs for all-cause mortality (adjusted HRs = 2.86, 95%CI: 2.01-4.07) and cardiorespiratory mortality (adjusted HRs = 2.86, 95%CI: 1.99-4.12). The association between age and mortality after diagnosis of COVID-19 due to both all-causes and cardiorespiratory mortality showed a consistent dose-response fashion. Institutionalization, disability, and socioeconomic status also showed a significant association with mortality. In conclusion, aging itself was the most important risk factor associated with mortality one year after diagnosis of COVID-19. People with disabilities, institutionalized or low socioeconomic status are significantly more likely to die after COVID-19.
000118750 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000118750 590__ $$a7.0$$b2023
000118750 591__ $$aGERIATRICS & GERONTOLOGY$$b6 / 74 = 0.081$$c2023$$dQ1$$eT1
000118750 594__ $$a14.6$$b2023
000118750 592__ $$a1.922$$b2023
000118750 593__ $$aCell Biology$$c2023$$dQ1
000118750 593__ $$aPathology and Forensic Medicine$$c2023$$dQ1
000118750 593__ $$aNeurology (clinical)$$c2023$$dQ1
000118750 593__ $$aGeriatrics and Gerontology$$c2023$$dQ1
000118750 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000118750 700__ $$0(orcid)0000-0002-7865-3429$$aLopez-Bueno, Ruben
000118750 700__ $$aTorres-Castro, Rodrigo
000118750 700__ $$aSoto-Carmona, Camilo
000118750 700__ $$aOrtega-Palavecinos, Maritza
000118750 700__ $$aPerez-Alenda, Sofia
000118750 700__ $$aSolis-Navarro, Lilian
000118750 700__ $$aDiaz-Cambronero, Oscar
000118750 700__ $$aMartinez-Arnau, Francisco M.
000118750 700__ $$aCalatayud, Joaquin
000118750 773__ $$g14, 1 (2023), 14-20$$pAging dis.$$tAging and disease$$x2152-5250
000118750 8564_ $$s514059$$uhttps://zaguan.unizar.es/record/118750/files/texto_completo.pdf$$yVersión publicada
000118750 8564_ $$s2845116$$uhttps://zaguan.unizar.es/record/118750/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000118750 909CO $$ooai:zaguan.unizar.es:118750$$particulos$$pdriver
000118750 951__ $$a2024-11-22-11:58:14
000118750 980__ $$aARTICLE