000118787 001__ 118787
000118787 005__ 20221006120648.0
000118787 0247_ $$2doi$$a10.1021/acs.biomac.9b00722
000118787 0248_ $$2sideral$$a112987
000118787 037__ $$aART-2019-112987
000118787 041__ $$aeng
000118787 100__ $$aGonzalez-Dominguez, José Miguel
000118787 245__ $$aUnique properties and behavior of nonmercerized type-ii cellulose nanocrystals as carbon nanotube biocompatible dispersants
000118787 260__ $$c2019
000118787 5060_ $$aAccess copy available to the general public$$fUnrestricted
000118787 5203_ $$aNanocellulose is increasingly being investigated as a paradigm of a sustainable nanomaterial because of its extraordinary physical and chemical properties, together with its renewable nature and worldwide abundance. The rich structural diversity of cellulose materials is represented by different crystalline allomorphs, from which types I and II stand out. While type I is naturally and ubiquitously present, type II is man-made and requires harsh and caustic synthesis conditions such as the so-called mercerization process. Here, we provide an optimal scenario to obtain either type-I or II nanocrystalline cellulose (NCC) by a mercerization-free method consisting only of the acid hydrolysis commonly used to produce nanocellulose from microcellulose. The possibility of having nonmercerized type-II NCC acquires a great relevance since this nanostructure shows particularly appealing properties. Moreover, an entangled and wrapped system arises when used as a dispersing agent for single-walled carbon nanotubes (SWCNTs), significantly different from that of type I. The biological testing of each NCC type and their respective SWCNT-NCC dispersions in human intestinal (Caco-2) cells reveals a general innocuous behavior in both cancer and normal stages of differentiation; however, the type-II-based SWCNT-NCC dispersions display cytotoxicity for cancer cells while enhancing mitochondrial metabolism of normal cells.
000118787 536__ $$9info:eu-repo/grantAgreement/ES/DGA-FEDER/A02-17R$$9info:eu-repo/grantAgreement/ES/DGA/T03-17R$$9info:eu-repo/grantAgreement/ES/MINECO-AEI/ENE2016-79282-C5-1-R$$9info:eu-repo/grantAgreement/ES/MINECO/BES-2017-080020
000118787 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000118787 590__ $$a6.092$$b2019
000118787 591__ $$aBIOCHEMISTRY & MOLECULAR BIOLOGY$$b42 / 297 = 0.141$$c2019$$dQ1$$eT1
000118787 591__ $$aPOLYMER SCIENCE$$b5 / 89 = 0.056$$c2019$$dQ1$$eT1
000118787 591__ $$aCHEMISTRY, ORGANIC$$b3 / 57 = 0.053$$c2019$$dQ1$$eT1
000118787 592__ $$a1.61$$b2019
000118787 593__ $$aBioengineering$$c2019$$dQ1
000118787 593__ $$aPolymers and Plastics$$c2019$$dQ1
000118787 593__ $$aMaterials Chemistry$$c2019$$dQ1
000118787 593__ $$aBiomaterials$$c2019$$dQ1
000118787 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000118787 700__ $$aAnson-Casaos, Alejandro
000118787 700__ $$0(orcid)0000-0002-5306-9365$$aGrasa, Laura$$uUniversidad de Zaragoza
000118787 700__ $$aAbenia, Luis
000118787 700__ $$aSalvador, Alba
000118787 700__ $$aColom, Eduardo
000118787 700__ $$0(orcid)0000-0003-4758-3998$$aMesonero, José E.$$uUniversidad de Zaragoza
000118787 700__ $$aGarcia-Bordeje, J.Enrique
000118787 700__ $$aBenito, Ana M.
000118787 700__ $$aMaser, Wolfgang K.
000118787 7102_ $$11005$$2410$$aUniversidad de Zaragoza$$bDpto. Farmacología y Fisiolog.$$cÁrea Fisiología
000118787 773__ $$g20, 8 (2019), 3147-3160$$pBiomacromolecules$$tBIOMACROMOLECULES$$x1525-7797
000118787 8564_ $$s5081715$$uhttps://zaguan.unizar.es/record/118787/files/texto_completo.pdf$$yPostprint
000118787 8564_ $$s1512930$$uhttps://zaguan.unizar.es/record/118787/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000118787 909CO $$ooai:zaguan.unizar.es:118787$$particulos$$pdriver
000118787 951__ $$a2022-10-06-10:03:07
000118787 980__ $$aARTICLE