118793 20240319080950.0 doi 10.1007/s00216-021-03755-0 sideral 126939 ART-2022-126939 eng Osorio, Jazmín Comparison of LC-ESI, DART, and ASAP for the analysis of oligomers migration from biopolymer food packaging materials in food (simulants) 2022 Access copy available to the general public Unrestricted Biopolymers based on polylactic acid (PLA) and starch have numerous advantages, such as coming from renewable sources or being compostable, though they can have deficiencies in mechanical properties, and for this reason, polyester resins are occasionally added to them in order to improve their properties. In this work, migration from a PLA sample and from another starch-based biopolymer to three different food simulants was studied. Attention was focused on the determination of oligomers. The analysis was first performed by ultraperformance liquid chromatography quadrupole-time-of-flight mass spectrometry (UPLC-Q-TOF–MS), which allowed the identification of the oligomers present in migration. Then, the samples were analyzed by two ambient desorption/ionization techniques directly coupled to mass spectrometry (ADI), direct analysis in real-time coupled to standardized voltage and pressure (DART-MS) and atmospheric pressure solids analysis probe (ASAP-MS). These methodologies were able to detect simultaneously the main oligomers migrants and their adducts in a very rapid and effective way. Nineteen different polyester oligomers, fourteen linear and five cyclic, composed of different combinations of adipic acid [AA], propylene glycol [PG], dipropylene glycol [DPG], 2, 2-dibutyl-1, 3-propanediol [DBPG], or isobutanol [i-BuOH] were detected in migration samples from PLA. In migration samples from starch-based biopolymer, fourteen oligomers from poly(butylene adipate co-terephthalate) polyester (PBAT) were identified, twelve cyclic and two linear. The results from ADI techniques showed that they are a very promising alternative tool to assess the safety and legal compliance of food packaging materials. Graphical abstract: [Figure not available: see fulltext.]. info:eu-repo/grantAgreement/ES/DGA-FEDER/T53-20R info:eu-repo/grantAgreement/ES/MINECO/RTI2018-097805-B-I00 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 4.3 2022 CHEMISTRY, ANALYTICAL 20 / 86 = 0.233 2022 Q1 T1 BIOCHEMICAL RESEARCH METHODS 18 / 77 = 0.234 2022 Q1 T1 0.676 2022 Biochemistry 2022 Q2 Analytical Chemistry 2022 Q2 7.5 2022 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Aznar, Margarita Universidad de Zaragoza (orcid)0000-0002-0759-9170 Nerín, Cristina Universidad de Zaragoza (orcid)0000-0003-2685-5739 Elliott, Christopher Chevallier, Olivier 2009 750 Universidad de Zaragoza Dpto. Química Analítica Área Química Analítica 414 (2022), 1335–1345 Anal. Bioanal. Chem. Analytical and Bioanalytical Chemistry 1618-2642 1681004 http://zaguan.unizar.es/record/118793/files/texto_completo.pdf Versión publicada 2499778 http://zaguan.unizar.es/record/118793/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:118793 articulos driver 2024-03-18-13:00:26 ARTICLE