000118901 001__ 118901 000118901 005__ 20240319081004.0 000118901 0247_ $$2doi$$a10.3390/ani12050622 000118901 0248_ $$2sideral$$a129453 000118901 037__ $$aART-2022-129453 000118901 041__ $$aeng 000118901 100__ $$aGonzález-Fandos, Elena 000118901 245__ $$aEffect of Intramuscularly Administered Oxytetracycline or Enrofloxacin on Vancomycin-Resistant Enterococci, Extended Spectrum Beta-Lactamase- and Carbapenemase-Producing Enterobacteriaceae in Pigs 000118901 260__ $$c2022 000118901 5060_ $$aAccess copy available to the general public$$fUnrestricted 000118901 5203_ $$aNowadays, there is a great concern about the prevalence of multidrug resistant Enterococcus spp. and Enterobacteriaceae in food-producing animals. The aim of this work was to evaluate the effect of oxytetracycline or enrofloxacin treatment on vancomycin-resistant enterococci (VRE), extended spectrum β-lactamase (ESBL) and carbapenemase-producing Enterobacteriaceae in pigs. A total of 26 piglets were received and distributed in three groups. Group 1 was treated with enrofloxacin (N = 12), group 2 with oxytetracycline (N = 10) and group 3 did not receive any treatment (control group) (N = 4). A higher number of vancomycin-resistant E. faecium were recovered compared to E. faecalis. In the pigs treated with enrofloxacin, vancomycin resistant E. faecium was found in a higher percentage of animals than in the control group. ESBL-producing E. coli was not detected in rectal samples from control animals. However, it was detected in 17–20% of animals treated with oxytetracycline on days 6 to 17 and in 17–50% of the animals treated with enrofloxacin. Carbapenemase-producing E. coli was isolated in animals treated with oxytetracycline, but not in animals treated with enrofloxacin or in the control group. This study highlights that the use of oxytetracycline or enrofloxacin in food-producing animals could select ESBL and carbapenemase-producing E. coli. Further studies shall be needed to validate the results obtained, considering a more robust and extended experimental design. 000118901 536__ $$9info:eu-repo/grantAgreement/EUR/INTERREG-V-A-POCTEFA/TESTACOS-EFA152/16 000118901 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000118901 590__ $$a3.0$$b2022 000118901 592__ $$a0.684$$b2022 000118901 591__ $$aVETERINARY SCIENCES$$b13 / 144 = 0.09$$c2022$$dQ1$$eT1 000118901 593__ $$aVeterinary (miscellaneous)$$c2022$$dQ1 000118901 591__ $$aAGRICULTURE, DAIRY & ANIMAL SCIENCE$$b12 / 62 = 0.194$$c2022$$dQ1$$eT1 000118901 593__ $$aAnimal Science and Zoology$$c2022$$dQ1 000118901 594__ $$a4.2$$b2022 000118901 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000118901 700__ $$aMartínez-Laorden, Alba 000118901 700__ $$aAbad-Fau, Ana 000118901 700__ $$0(orcid)0000-0002-4213-2904$$aSevilla, Eloisa$$uUniversidad de Zaragoza 000118901 700__ $$0(orcid)0000-0002-2746-3932$$aBolea, Rosa$$uUniversidad de Zaragoza 000118901 700__ $$0(orcid)0000-0003-3850-9833$$aSerrano, María Jesús 000118901 700__ $$0(orcid)0000-0001-9907-2941$$aMitjana, Olga$$uUniversidad de Zaragoza 000118901 700__ $$0(orcid)0000-0001-6178-9891$$aBonastre, Cristina$$uUniversidad de Zaragoza 000118901 700__ $$0(orcid)0000-0003-0296-1617$$aLaborda, Alicia$$uUniversidad de Zaragoza 000118901 700__ $$0(orcid)0000-0001-6964-7011$$aFalceto, María Victoria$$uUniversidad de Zaragoza 000118901 700__ $$0(orcid)0000-0002-0238-6328$$aPagán, Rafael$$uUniversidad de Zaragoza 000118901 7102_ $$11009$$2773$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Sanidad Animal 000118901 7102_ $$11009$$2617$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Medicina y Cirugía Animal 000118901 7102_ $$12008$$2780$$aUniversidad de Zaragoza$$bDpto. Produc.Animal Cienc.Ali.$$cÁrea Tecnología de Alimentos 000118901 773__ $$g12, 5 (2022), 622 [19 pp.]$$pAnimals (Basel)$$tAnimals$$x2076-2615 000118901 8564_ $$s569934$$uhttps://zaguan.unizar.es/record/118901/files/texto_completo.pdf$$yVersión publicada 000118901 8564_ $$s2744430$$uhttps://zaguan.unizar.es/record/118901/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000118901 909CO $$ooai:zaguan.unizar.es:118901$$particulos$$pdriver 000118901 951__ $$a2024-03-18-14:28:37 000118901 980__ $$aARTICLE