118901 20250131161522.0 doi 10.3390/ani12050622 sideral 129453 ART-2022-129453 eng González-Fandos, Elena Effect of Intramuscularly Administered Oxytetracycline or Enrofloxacin on Vancomycin-Resistant Enterococci, Extended Spectrum Beta-Lactamase- and Carbapenemase-Producing Enterobacteriaceae in Pigs 2022 Access copy available to the general public Unrestricted Nowadays, there is a great concern about the prevalence of multidrug resistant Enterococcus spp. and Enterobacteriaceae in food-producing animals. The aim of this work was to evaluate the effect of oxytetracycline or enrofloxacin treatment on vancomycin-resistant enterococci (VRE), extended spectrum β-lactamase (ESBL) and carbapenemase-producing Enterobacteriaceae in pigs. A total of 26 piglets were received and distributed in three groups. Group 1 was treated with enrofloxacin (N = 12), group 2 with oxytetracycline (N = 10) and group 3 did not receive any treatment (control group) (N = 4). A higher number of vancomycin-resistant E. faecium were recovered compared to E. faecalis. In the pigs treated with enrofloxacin, vancomycin resistant E. faecium was found in a higher percentage of animals than in the control group. ESBL-producing E. coli was not detected in rectal samples from control animals. However, it was detected in 17–20% of animals treated with oxytetracycline on days 6 to 17 and in 17–50% of the animals treated with enrofloxacin. Carbapenemase-producing E. coli was isolated in animals treated with oxytetracycline, but not in animals treated with enrofloxacin or in the control group. This study highlights that the use of oxytetracycline or enrofloxacin in food-producing animals could select ESBL and carbapenemase-producing E. coli. Further studies shall be needed to validate the results obtained, considering a more robust and extended experimental design. info:eu-repo/grantAgreement/EUR/INTERREG-V-A-POCTEFA/TESTACOS-EFA152/16 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 3.0 2022 VETERINARY SCIENCES 13 / 144 = 0.09 2022 Q1 T1 AGRICULTURE, DAIRY & ANIMAL SCIENCE 12 / 62 = 0.194 2022 Q1 T1 0.684 2022 Veterinary (miscellaneous) 2022 Q1 Animal Science and Zoology 2022 Q1 4.2 2022 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Martínez-Laorden, Alba Abad-Fau, Ana Universidad de Zaragoza (orcid)0000-0003-0990-9563 Sevilla, Eloisa Universidad de Zaragoza (orcid)0000-0002-4213-2904 Bolea, Rosa Universidad de Zaragoza (orcid)0000-0002-2746-3932 Serrano, María Jesús (orcid)0000-0003-3850-9833 Mitjana, Olga Universidad de Zaragoza (orcid)0000-0001-9907-2941 Bonastre, Cristina Universidad de Zaragoza (orcid)0000-0001-6178-9891 Laborda, Alicia Universidad de Zaragoza (orcid)0000-0003-0296-1617 Falceto, María Victoria Universidad de Zaragoza (orcid)0000-0001-6964-7011 Pagán, Rafael Universidad de Zaragoza (orcid)0000-0002-0238-6328 1009 773 Universidad de Zaragoza Dpto. Patología Animal Área Sanidad Animal 1009 617 Universidad de Zaragoza Dpto. Patología Animal Área Medicina y Cirugía Animal 2008 780 Universidad de Zaragoza Dpto. Produc.Animal Cienc.Ali. Área Tecnología de Alimentos 12, 5 (2022), 622 [19 pp.] Animals (Basel) Animals 2076-2615 569934 http://zaguan.unizar.es/record/118901/files/texto_completo.pdf Versión publicada 2744430 http://zaguan.unizar.es/record/118901/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:118901 articulos driver 2025-01-31-16:13:26 ARTICLE