000118938 001__ 118938
000118938 005__ 20240319081009.0
000118938 0247_ $$2doi$$a10.3390/app12136438
000118938 0248_ $$2sideral$$a130068
000118938 037__ $$aART-2022-130068
000118938 041__ $$aeng
000118938 100__ $$aAlbors, C.
000118938 245__ $$aMeshless electrophysiological modeling of cardiac resynchronization therapy—benchmark analysis with finite-element methods in experimental data
000118938 260__ $$c2022
000118938 5060_ $$aAccess copy available to the general public$$fUnrestricted
000118938 5203_ $$aComputational models of cardiac electrophysiology are promising tools for reducing the rates of non-response patients suitable for cardiac resynchronization therapy (CRT) by optimizing electrode placement. The majority of computational models in the literature are mesh-based, primarily using the finite element method (FEM). The generation of patient-specific cardiac meshes has traditionally been a tedious task requiring manual intervention and hindering the modeling of a large number of cases. Meshless models can be a valid alternative due to their mesh quality independence. The organization of challenges such as the CRT-EPiggy19, providing unique experimental data as open access, enables benchmarking analysis of different cardiac computational modeling solutions with quantitative metrics. We present a benchmark analysis of a meshless-based method with finite-element methods for the prediction of cardiac electrical patterns in CRT, based on a subset of the CRT-EPiggy19 dataset. A data assimilation strategy was designed to personalize the most relevant parameters of the electrophysiological simulations and identify the optimal CRT lead configuration. The simulation results obtained with the meshless model were equivalent to FEM, with the most relevant aspect for accurate CRT predictions being the parameter personalization strategy (e.g., regional conduction velocity distribution, including the Purkinje system and CRT lead distribution). © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
000118938 536__ $$9info:eu-repo/grantAgreement/ES/DGA/LMP94_21$$9info:eu-repo/grantAgreement/ES/MICINN-FEDER/PID2019-105674RB-I00$$9info:eu-repo/grantAgreement/ES/MICINN-REDINSCOR-RD06-003-008$$9info:eu-repo/grantAgreement/ES/MICINN/TIN2011-28067$$9info:eu-repo/grantAgreement/ES/MINECO/DPI2016-75799-R
000118938 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000118938 590__ $$a2.7$$b2022
000118938 592__ $$a0.492$$b2022
000118938 591__ $$aPHYSICS, APPLIED$$b78 / 160 = 0.488$$c2022$$dQ2$$eT2
000118938 591__ $$aENGINEERING, MULTIDISCIPLINARY$$b42 / 90 = 0.467$$c2022$$dQ2$$eT2
000118938 591__ $$aCHEMISTRY, MULTIDISCIPLINARY$$b100 / 178 = 0.562$$c2022$$dQ3$$eT2
000118938 591__ $$aMATERIALS SCIENCE, MULTIDISCIPLINARY$$b208 / 343 = 0.606$$c2022$$dQ3$$eT2
000118938 593__ $$aFluid Flow and Transfer Processes$$c2022$$dQ2
000118938 593__ $$aMaterials Science (miscellaneous)$$c2022$$dQ2
000118938 593__ $$aEngineering (miscellaneous)$$c2022$$dQ2
000118938 593__ $$aInstrumentation$$c2022$$dQ2
000118938 593__ $$aProcess Chemistry and Technology$$c2022$$dQ3
000118938 593__ $$aComputer Science Applications$$c2022$$dQ3
000118938 594__ $$a4.5$$b2022
000118938 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000118938 700__ $$aLluch, È.
000118938 700__ $$aGomez, J. F.
000118938 700__ $$aCedilnik, N.
000118938 700__ $$aMountris, K. A.
000118938 700__ $$aMansi, T.
000118938 700__ $$aKhamzin, S.
000118938 700__ $$aDokuchaev, A.
000118938 700__ $$aSolovyova, O.
000118938 700__ $$0(orcid)0000-0002-1960-407X$$aPueyo, E.$$uUniversidad de Zaragoza
000118938 700__ $$aSermesant, M.
000118938 700__ $$aSebastian, R.
000118938 700__ $$aMorales, H. G.
000118938 700__ $$aCamara, O.
000118938 7102_ $$15008$$2800$$aUniversidad de Zaragoza$$bDpto. Ingeniería Electrón.Com.$$cÁrea Teoría Señal y Comunicac.
000118938 773__ $$g12, 13 (2022), 6438 [27 pp]$$pAppl. sci.$$tApplied Sciences (Switzerland)$$x2076-3417
000118938 8564_ $$s1440573$$uhttps://zaguan.unizar.es/record/118938/files/texto_completo.pdf$$yVersión publicada
000118938 8564_ $$s2873537$$uhttps://zaguan.unizar.es/record/118938/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000118938 909CO $$ooai:zaguan.unizar.es:118938$$particulos$$pdriver
000118938 951__ $$a2024-03-18-14:59:21
000118938 980__ $$aARTICLE