000119671 001__ 119671
000119671 005__ 20230519145542.0
000119671 0247_ $$2doi$$a10.1159/000514884
000119671 0248_ $$2sideral$$a126500
000119671 037__ $$aART-2021-126500
000119671 041__ $$aeng
000119671 100__ $$aGomez-Roig, MD
000119671 245__ $$aEnvironmental exposure during pregnancy: influence on prenatal development and early life: a comprehensive review
000119671 260__ $$c2021
000119671 5060_ $$aAccess copy available to the general public$$fUnrestricted
000119671 5203_ $$aPreconception and prenatal exposure to environmental contaminants may affect future health. Pregnancy and early life are critical sensitive windows of susceptibility. The aim of this review was to summarize current evidence on the toxic effects of environment exposure during pregnancy, the neonatal period, and childhood. Alcohol use is related to foetal alcohol spectrum disorders, foetal alcohol syndrome being its most extreme form. Smoking is associated with placental abnormalities, preterm birth, stillbirth, or impaired growth and development, as well as with intellectual impairment, obesity, and cardiovascular diseases later in life. Negative birth outcomes have been linked to the use of drugs of abuse. Pregnant and lactating women are exposed to endocrine-disrupting chemicals and heavy metals present in foodstuffs, which may alter hormones in the body. Prenatal exposure to these compounds has been associated with pre-eclampsia and intrauterine growth restriction, preterm birth, and thyroid function. Metals can accumulate in the placenta, causing foetal growth restriction. Evidence on the effects of air pollutants on pregnancy is constantly growing, for example, preterm birth, foetal growth restriction, increased uterine vascular resistance, impaired placental vascularization, increased gestational diabetes, and reduced telomere length. The advantages of breastfeeding outweigh any risks from contaminants. However, it is important to assess health outcomes of toxic exposures via breastfeeding. Initial studies suggest an association between pre-eclampsia and environmental noise, particularly with early-onset pre-eclampsia. There is rising evidence of the negative effects of environmental contaminants following exposure during pregnancy and breastfeeding, which should be considered a major public health issue.
000119671 536__ $$9info:eu-repo/grantAgreement/ES/RETICS-ISCIII-ERDF/RD16-0022
000119671 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000119671 590__ $$a2.208$$b2021
000119671 591__ $$aOBSTETRICS & GYNECOLOGY$$b66 / 85 = 0.776$$c2021$$dQ4$$eT3
000119671 592__ $$a0.935$$b2021
000119671 593__ $$aEmbryology$$c2021$$dQ1
000119671 593__ $$aRadiology, Nuclear Medicine and Imaging$$c2021$$dQ1
000119671 593__ $$aPediatrics, Perinatology and Child Health$$c2021$$dQ1
000119671 593__ $$aMedicine (miscellaneous)$$c2021$$dQ1
000119671 594__ $$a4.2$$b2021
000119671 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/submittedVersion
000119671 700__ $$aPascal, R
000119671 700__ $$aCahuana, MJ
000119671 700__ $$aGarcia-Algar, O
000119671 700__ $$aSebastiani, G
000119671 700__ $$aAndreu-Fernandez, V
000119671 700__ $$aMartinez, L
000119671 700__ $$0(orcid)0000-0002-7985-9912$$aRodriguez, G$$uUniversidad de Zaragoza
000119671 700__ $$aIglesia, I
000119671 700__ $$aOrtiz-Arrabal, O
000119671 700__ $$aMesa, MD
000119671 700__ $$aCabero, MJ
000119671 700__ $$aGuerra, L
000119671 700__ $$aLlurba, E
000119671 700__ $$aDominguez, C
000119671 700__ $$aZanini, MJ
000119671 700__ $$aForaster, M
000119671 700__ $$aLarque, E
000119671 700__ $$aCabanas, F
000119671 700__ $$aLopez-Azorin, M
000119671 700__ $$aPerez, A
000119671 700__ $$aLoureiro, B
000119671 700__ $$aPallas-Alonso, CR
000119671 700__ $$aEscuder-Vieco, D
000119671 700__ $$aVento, M
000119671 7102_ $$11011$$2670$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Pediatría
000119671 773__ $$g48, 4 (2021), 245–257$$pFetal diagn. ther.$$tFetal Diagnosis and Therapy$$x1015-3837
000119671 8564_ $$s673552$$uhttps://zaguan.unizar.es/record/119671/files/texto_completo.pdf$$yPreprint
000119671 8564_ $$s1908714$$uhttps://zaguan.unizar.es/record/119671/files/texto_completo.jpg?subformat=icon$$xicon$$yPreprint
000119671 909CO $$ooai:zaguan.unizar.es:119671$$particulos$$pdriver
000119671 951__ $$a2023-05-18-15:41:14
000119671 980__ $$aARTICLE