000119706 001__ 119706
000119706 005__ 20240319081014.0
000119706 0247_ $$2doi$$a10.1038/s41598-022-22419-2
000119706 0248_ $$2sideral$$a130492
000119706 037__ $$aART-2022-130492
000119706 041__ $$aeng
000119706 100__ $$aPino-Otín, María Rosa
000119706 245__ $$aAntibiotic properties of satureja montana l. hydrolate in bacteria and fungus of clinical interest and its impact in non-target environmental microorganisms
000119706 260__ $$c2022
000119706 5060_ $$aAccess copy available to the general public$$fUnrestricted
000119706 5203_ $$aThe aim of this study was to analyse the microbicidal and microbiostatic activity of S. montana hydrolate L., the water-soluble fraction of the hydro-distillation process used to obtain the essential oil, on 14 Gram-positive and Gram-negative bacteria and a fungus of clinical interest. To consider whether this hydrolate is a more environmentally friendly alternative to traditional antibiotics, its effect on non-target microorganisms in the aquatic and terrestrial environment was analysed using natural soil and river microorganism communities, characterized through 16S rRNA gene sequencing. Results showed that S. montana hydrolate was especially effective (25% v/v concentration) against Pasteurella aerogenes, Streptococcus agalactiae and Acinetobacter baumannii (priority 1, WHO). It was also a microbicide for a further 7 bacterial strains and the fungus Candida albicans (50% v/v concentration). The river and soil communities exposed to the hydrolate showed a decrease in their growth, as well as a decrease in their ability to metabolize polymers and carbohydrates (soil microorganisms) and polymers, carboxylic and ketone acids (river microorganisms). Hydrolates could be an alternative to conventional antibiotics, but their impact on the environment must be taken into account.
000119706 536__ $$9info:eu-repo/grantAgreement/ES/DGA/E39-20R
000119706 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000119706 590__ $$a4.6$$b2022
000119706 592__ $$a0.973$$b2022
000119706 591__ $$aMULTIDISCIPLINARY SCIENCES$$b22 / 73 = 0.301$$c2022$$dQ2$$eT1
000119706 593__ $$aMultidisciplinary$$c2022$$dQ1
000119706 594__ $$a7.5$$b2022
000119706 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000119706 700__ $$aGan, Cristina
000119706 700__ $$0(orcid)0000-0001-8511-5218$$aTerrado, Eva$$uUniversidad de Zaragoza
000119706 700__ $$aSanz, María Angeles
000119706 700__ $$aBallestero, Diego
000119706 700__ $$aLanga, Elisa
000119706 7102_ $$14013$$2205$$aUniversidad de Zaragoza$$bDpto. Didácticas Específicas$$cÁrea Didáctica Ciencias Exper.
000119706 773__ $$g12 (2022), 18460 [17 pp]$$pSci. rep. (Nat. Publ. Group)$$tScientific reports (Nature Publishing Group)$$x2045-2322
000119706 8564_ $$s2061652$$uhttps://zaguan.unizar.es/record/119706/files/texto_completo.pdf$$yVersión publicada
000119706 8564_ $$s2420169$$uhttps://zaguan.unizar.es/record/119706/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000119706 909CO $$ooai:zaguan.unizar.es:119706$$particulos$$pdriver
000119706 951__ $$a2024-03-18-15:26:33
000119706 980__ $$aARTICLE