000119728 001__ 119728
000119728 005__ 20240705134139.0
000119728 0247_ $$2doi$$a10.1016/j.pulmoe.2022.09.007
000119728 0248_ $$2sideral$$a130515
000119728 037__ $$aART-2022-130515
000119728 041__ $$aeng
000119728 100__ $$aMey, R.
000119728 245__ $$aHandgrip strength and respiratory disease mortality: Longitudinal analyses from SHARE
000119728 260__ $$c2022
000119728 5060_ $$aAccess copy available to the general public$$fUnrestricted
000119728 5203_ $$aBackground: While the association between handgrip strength and all-cause mortality is more deeply explored, no previous studies have been specifically focused on handgrip strength and respiratory disease mortality. The purpose of the study was to investigate the association between handgrip strength and respiratory disease mortality in a large representative sample. Methods: Individuals aged 50 or over from 27 European countries and Israel participated in this longitudinal study. Data on handgrip strength and all-cause and respiratory disease mortality were retrieved from the Survey of Health, Ageing and Retirement in Europe (SHARE) waves 1, 2, 4, 5, 6 and 7. We estimated the sub hazard ratios (SHRs) for respiratory disease mortality using a Fine-Gray sub-distribution method with both time-varying exposure and covariates and mortality due to other causes as competing risk. Furthermore, we assessed dose‐response associations of handgrip strength (modelled as a continuous exposure) with respiratory disease mortality using restricted cubic splines and estimated hazard ratios (HRs). Results: We included 60,883 men and 74,904 women with a mean age of 63.6 (SD 9.7) years at study entry. During a median (interquartile range) of 7.4 years of follow-up 565 (0.4%) participants died due to respiratory diseases. The increase of 1 single kg of handgrip strength showed a 6% incidence reduction on respiratory disease mortality (SHR, 0.94; 95%CI, 0.92-0.96) after adjusting for potential confounders. Furthermore, each kg increase of handgrip strength reduced respiratory disease mortality risk in a dose-response fashion and a significant threshold for values of 41 kg (HR, 0.49; 95%CI, 0.26-0.92) and higher was identified. Conclusions: Higher handgrip strength is associated with lower mortality due to respiratory disease. Intervention studies are needed to determine whether strength training in respiratory disease patients can prevent premature mortality.
000119728 536__ $$9info:eu-repo/grantAgreement/EC/FP7/211909/EU/Upgrading the Survey of Health, Ageing and Retirement in Europe – preparatory phase/SHARE-PREP$$9info:eu-repo/grantAgreement/EC/FP7/227822/EU/Longitudinal Enhancement and Access imProvement of the SHARE infrastructure/SHARE_LEAP$$9info:eu-repo/grantAgreement/EC/FP7/261982/EU/Multinational Advancement of Research Infrastructures on Ageing/SHARE_M4$$9info:eu-repo/grantAgreement/EC/FP7/283646/EU/Data Service Infrastructure for the Social Sciences and Humanities/DASISH$$9info:eu-repo/grantAgreement/EC/HS/QLK6-CT-2001-00360/EU/Survey on health, ageing and retirement in europe (SHARE)/SHARE$$9info:eu-repo/grantAgreement/EC/H2020/654221/EU/Synergies for Europe's Research Infrastructures in the Social Sciences/SERISS$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 654221-SERISS$$9info:eu-repo/grantAgreement/EC/H2020/676536/EU/Achieving world-class standards in all SHARE countries/SHARE-DEV3$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 676536-SHARE-DEV3$$9info:eu-repo/grantAgreement/EC/H2020/823782/EU/Social Sciences & Humanities Open Cloud/SSHOC$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 823782-SSHOC$$9info:eu-repo/grantAgreement/EC/H2020/870628/EU/Cohesion in further developing and innovating SHARE across all 28 member countries/SHARE-COHESION$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 870628-SHARE-COHESION
000119728 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000119728 590__ $$a11.7$$b2022
000119728 592__ $$a1.641$$b2022
000119728 591__ $$aRESPIRATORY SYSTEM$$b5 / 66 = 0.076$$c2022$$dQ1$$eT1
000119728 593__ $$aPulmonary and Respiratory Medicine$$c2022$$dQ1
000119728 594__ $$a13.0$$b2022
000119728 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000119728 700__ $$aCalatayud, J.
000119728 700__ $$aCasaña, J.
000119728 700__ $$aTorres-Castro, R.
000119728 700__ $$aCuenca-Martínez, F.
000119728 700__ $$aSuso-Martí, L.
000119728 700__ $$aAndersen, L.L.
000119728 700__ $$0(orcid)0000-0002-7865-3429$$aLópez-Bueno, R.
000119728 773__ $$pPulmonolgy$$tPulmonolgy$$x2531-0429
000119728 8564_ $$s606942$$uhttps://zaguan.unizar.es/record/119728/files/texto_completo.pdf$$yPostprint
000119728 8564_ $$s2328020$$uhttps://zaguan.unizar.es/record/119728/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000119728 909CO $$ooai:zaguan.unizar.es:119728$$particulos$$pdriver
000119728 951__ $$a2024-07-05-12:46:19
000119728 980__ $$aARTICLE