Resumen: We report the results of 6 years (2013–2018) of measurements of 222Rn air concentration, relative humidity, atmospheric pressure and temperature in the halls A, B and C of the Canfranc Underground Laboratory (LSC). We have calculated all the Pearson correlation coefficients among these parameters and we have found a positive correlation between the 222Rn concentration and the relative humidity. Both correlated variables show a seasonal periodicity. The joint analysis of laboratory data and 4 years (2015–2018) of the meteorological variables outside the laboratory shows the correlation between the 222Rn concentration and the outside temperature. The collected information stresses the relevance of designing good Rn-mitigation strategies in current and future experiments at LSC; in particular, we have checked for two years (2017–2018) the good performance of the mitigation procedure of the ANAIS-112 experiment. Finally, we have monitored (2019–2021) for 2 years of live time, the radon-free air provided by the radon abatement system installed in the laboratory. Idioma: Inglés DOI: 10.1140/epjc/s10052-022-10859-z Año: 2022 Publicado en: The European Physical Journal C 82, 891 (2022), 10 ISSN: 1434-6044 Factor impacto JCR: 4.4 (2022) Categ. JCR: PHYSICS, PARTICLES & FIELDS rank: 8 / 29 = 0.276 (2022) - Q2 - T1 Factor impacto CITESCORE: 8.3 - Physics and Astronomy (Q1) - Engineering (Q1)