000119866 001__ 119866
000119866 005__ 20240319081012.0
000119866 0247_ $$2doi$$a10.3390/ijms232012424
000119866 0248_ $$2sideral$$a130790
000119866 037__ $$aART-2022-130790
000119866 041__ $$aeng
000119866 100__ $$aFeiner Solís, Ángela
000119866 245__ $$aThe Effects of Vitamin D Supplementation in COVID-19 Patients: A Systematic Review
000119866 260__ $$c2022
000119866 5060_ $$aAccess copy available to the general public$$fUnrestricted
000119866 5203_ $$aVitamin D has an immune-modulating effect on respiratory tract infections. For this reason, it has been proposed as part of the treatment in COVID-19. Furthermore, vitamin D deficiency has been associated with worse clinical outcomes of this disease. The aim of this systematic review was to determine whether vitamin D supplementation modifies the disease course. Therefore, eleven studies involving randomised clinical trials are analysed, in which groups of COVID-19 patients with or without vitamin D supplementation as part of the treatment are compared. A control group was treated with best available therapy, and in some of the clinical trials, also with a placebo. According to the outcomes, it seems that patients benefit from receiving a daily or maintained in time vitamin D dose regardless of vitamin D serum levels at the beginning of the trial. The administration of a single vitamin D dose does not seem to have any effect on the health status of these patients. However, the outcomes are heterogeneous and larger clinical trials are necessary.
000119866 536__ $$9info:eu-repo/grantAgreement/ES/DGA/A05-20R
000119866 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000119866 590__ $$a5.6$$b2022
000119866 592__ $$a1.154$$b2022
000119866 591__ $$aBIOCHEMISTRY & MOLECULAR BIOLOGY$$b66 / 285 = 0.232$$c2022$$dQ1$$eT1
000119866 593__ $$aMedicine (miscellaneous)$$c2022$$dQ1
000119866 591__ $$aCHEMISTRY, MULTIDISCIPLINARY$$b52 / 178 = 0.292$$c2022$$dQ2$$eT1
000119866 593__ $$aPhysical and Theoretical Chemistry$$c2022$$dQ1
000119866 593__ $$aComputer Science Applications$$c2022$$dQ1
000119866 593__ $$aInorganic Chemistry$$c2022$$dQ1
000119866 593__ $$aSpectroscopy$$c2022$$dQ1
000119866 593__ $$aOrganic Chemistry$$c2022$$dQ1
000119866 593__ $$aMolecular Biology$$c2022$$dQ2
000119866 593__ $$aCatalysis$$c2022$$dQ2
000119866 594__ $$a7.8$$b2022
000119866 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000119866 700__ $$aAvedillo Salas, Ana$$uUniversidad de Zaragoza
000119866 700__ $$0(orcid)0000-0003-4071-1467$$aLuesma Bartolomé, María José$$uUniversidad de Zaragoza
000119866 700__ $$0(orcid)0000-0002-1275-2600$$aSantander Ballestín, Sonia$$uUniversidad de Zaragoza
000119866 7102_ $$11003$$2027$$aUniversidad de Zaragoza$$bDpto. Anatom.Histolog.Humanas$$cArea Anatom.Embriol.Humana
000119866 7102_ $$11012$$2315$$aUniversidad de Zaragoza$$bDpto. Farmac.Fisiol.y Med.L.F.$$cÁrea Farmacología
000119866 773__ $$g23, 20 (2022), 12424 [15 pp.]$$pInt. j. mol. sci.$$tInternational Journal of Molecular Sciences$$x1661-6596
000119866 8564_ $$s1196260$$uhttps://zaguan.unizar.es/record/119866/files/texto_completo.pdf$$yVersión publicada
000119866 8564_ $$s2670113$$uhttps://zaguan.unizar.es/record/119866/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000119866 909CO $$ooai:zaguan.unizar.es:119866$$particulos$$pdriver
000119866 951__ $$a2024-03-18-15:13:26
000119866 980__ $$aARTICLE