000119873 001__ 119873 000119873 005__ 20240319081013.0 000119873 0247_ $$2doi$$a10.3389/fpsyg.2022.976661 000119873 0248_ $$2sideral$$a130699 000119873 037__ $$aART-2022-130699 000119873 041__ $$aeng 000119873 100__ $$aPeláez, Trinidad 000119873 245__ $$aApplication of the unified protocol for the transdiagnostic treatment of comorbid emotional disorders in patients with ultra-high risk of developing psychosis: A randomized trial study protocol 000119873 260__ $$c2022 000119873 5060_ $$aAccess copy available to the general public$$fUnrestricted 000119873 5203_ $$aCognitive Behavioral Therapy is delivered in most of the early intervention services for psychosis in different countries around the world. This approach has been demonstrated to be effective in decreasing or at least delaying the onset of psychosis. However, none of them directly affect the comorbidity of these types of patients that is often the main cause of distress and dysfunctionality. The Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders (UP) is a psychological intervention that combines cognitive-behavioral and third-generation techniques that address emotional dysregulation as an underlying mechanism that these disorders have in common. The application of this intervention could improve the comorbid emotional symptoms of these patients.Materials and methodsThe study is a randomized controlled trial in which one group receives immediate UP plus standard intervention and the other is placed on a waiting list to receive UP 7 months later, in addition to standard care in one of our early psychosis programs. The sample will be 42 patients with UHR for psychosis with comorbid emotional symptoms. The assessment is performed at baseline, at the end of treatment, and at 3-months’ follow-up, and includes: general psychopathology, anxiety and depression, positive and negative emotions, emotional dysregulation, personality, functionality, quality of life, cognitive distortions, insight, and satisfaction with the UP intervention.DiscussionThis will be the first study of the efficacy, acceptability, and viability of the UP in a sample of young adults with UHR. The results of this study may have clinical implications, contributing to improving the model of care for young people who consult for underlying psychotic, anxiety, and/or depressive symptoms that can lead to high distress and dysfunctionality.Clinical trial registration[https://clinicaltrials.gov/], identifier [NCT04929938]. 000119873 536__ $$9info:eu-repo/grantAgreement/ES/DGA-FEDER/S31-20D 000119873 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000119873 590__ $$a3.8$$b2022 000119873 592__ $$a0.891$$b2022 000119873 591__ $$aPSYCHOLOGY, MULTIDISCIPLINARY$$b34 / 147 = 0.231$$c2022$$dQ1$$eT1 000119873 593__ $$aPsychology (miscellaneous)$$c2022$$dQ2 000119873 594__ $$a4.5$$b2022 000119873 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000119873 700__ $$aLópez-Carrillero, Raquel 000119873 700__ $$aFerrer-Quintero, Marta 000119873 700__ $$aOchoa, Susana 000119873 700__ $$0(orcid)0000-0002-7293-318X$$aOsma, Jorge$$uUniversidad de Zaragoza 000119873 7102_ $$14009$$2680$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Person.Eval.Trat.Psicoló. 000119873 773__ $$g13 (2022), 976661 [8 pp.]$$pFront. psychol.$$tFrontiers in Psychology$$x1664-1078 000119873 8564_ $$s326725$$uhttps://zaguan.unizar.es/record/119873/files/texto_completo.pdf$$yVersión publicada 000119873 8564_ $$s2145452$$uhttps://zaguan.unizar.es/record/119873/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000119873 909CO $$ooai:zaguan.unizar.es:119873$$particulos$$pdriver 000119873 951__ $$a2024-03-18-15:20:05 000119873 980__ $$aARTICLE