000119897 001__ 119897
000119897 005__ 20240319081016.0
000119897 0247_ $$2doi$$a10.3390/biomedicines10092314
000119897 0248_ $$2sideral$$a130793
000119897 037__ $$aART-2022-130793
000119897 041__ $$aeng
000119897 100__ $$0(orcid)0000-0003-1234-9712$$aFernández-Espinosa, Guisela
000119897 245__ $$aChoroidal and Retinal Thicknesses in Type 2 Diabetes Mellitus with Moderate Diabetic Retinopathy Measured by Swept Source OCT
000119897 260__ $$c2022
000119897 5060_ $$aAccess copy available to the general public$$fUnrestricted
000119897 5203_ $$aBackground: To study choroidal thickness (CT) in type 2 diabetes mellitus (DM2) patients with moderate diabetic retinopathy (DR) and to correlate with changes in retinal thickness (RT) with swept-source OCT (SS-OCT) compared to healthy subjects. Methods: Fifty-four DM2 patients with moderate DR without diabetic macular edema (DME) and 73 age-matched healthy subjects were evaluated using SS-OCT to measure changes in total RT and CT in the nine areas of the Early Treatment Diabetic Retinopathy Study (ETDRS) macular grid. Results: The mean age was 64.06 ± 11.98 years and 60.79 ± 8.62 years in the diabetic and control groups, respectively. Total RT showed statistically significant differences in the temporal inner area, with higher values in the DM2 group (p = 0.010). CT did not show differences between the groups. There was a significant negative correlation between RT and age in all of the outer ETDRS areas and a positive significant correlation in the central area for the DM2 group. There was also a negative significant correlation between CT and age in all of the ETDRS areas except for the inferior inner area. In the DM2 group, a negative correlation was observed between RT and CT in the central area (p = 0.039) and in both horizontal parafoveal areas (temporal inner, p = 0.028; nasal inner, p= 0.003). Conclusion: DM2 patients with moderate DR have no changes with regard to CT. Both CT and RT decreased with age in DM2, showing a negative correlation between these factors in the central and horizontal parafoveal areas of the ETDRS grid.
000119897 536__ $$9info:eu-repo/grantAgreement/ES/DGA/B08-20R$$9info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI20-00740
000119897 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000119897 590__ $$a4.7$$b2022
000119897 592__ $$a0.897$$b2022
000119897 591__ $$aPHARMACOLOGY & PHARMACY$$b68 / 278 = 0.245$$c2022$$dQ1$$eT1
000119897 593__ $$aMedicine (miscellaneous)$$c2022$$dQ1
000119897 591__ $$aBIOCHEMISTRY & MOLECULAR BIOLOGY$$b92 / 285 = 0.323$$c2022$$dQ2$$eT1
000119897 593__ $$aBiochemistry, Genetics and Molecular Biology (miscellaneous)$$c2022$$dQ2
000119897 591__ $$aMEDICINE, RESEARCH & EXPERIMENTAL$$b54 / 136 = 0.397$$c2022$$dQ2$$eT2
000119897 594__ $$a3.7$$b2022
000119897 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000119897 700__ $$0(orcid)0000-0003-2710-1875$$aOrduna-Hospital, Elvira$$uUniversidad de Zaragoza
000119897 700__ $$aBoned-Murillo, Ana
000119897 700__ $$aDiaz-Barreda, Maria Dolores
000119897 700__ $$0(orcid)0000-0002-5621-1937$$aSanchez-Cano, Ana$$uUniversidad de Zaragoza
000119897 700__ $$aSopeña-Pinilla, María
000119897 700__ $$0(orcid)0000-0003-0349-9997$$aPinilla, Isabel$$uUniversidad de Zaragoza
000119897 7102_ $$11013$$2646$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Oftalmología
000119897 7102_ $$12002$$2647$$aUniversidad de Zaragoza$$bDpto. Física Aplicada$$cÁrea Óptica
000119897 773__ $$g10, 9 (2022), 2314 [10 pp.]$$tBiomedicines$$x2227-9059
000119897 8564_ $$s4627227$$uhttps://zaguan.unizar.es/record/119897/files/texto_completo.pdf$$yVersión publicada
000119897 8564_ $$s2791852$$uhttps://zaguan.unizar.es/record/119897/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000119897 909CO $$ooai:zaguan.unizar.es:119897$$particulos$$pdriver
000119897 951__ $$a2024-03-18-15:36:25
000119897 980__ $$aARTICLE