000120152 001__ 120152
000120152 005__ 20240319081003.0
000120152 0247_ $$2doi$$a10.1113/JP283398
000120152 0248_ $$2sideral$$a131031
000120152 037__ $$aART-2022-131031
000120152 041__ $$aeng
000120152 100__ $$aZicher, Blanka
000120152 245__ $$aBeta inputs to motor neurons do not directly contribute to volitional force modulation
000120152 260__ $$c2022
000120152 5060_ $$aAccess copy available to the general public$$fUnrestricted
000120152 5203_ $$aNeural oscillatory activity in the beta band (13–30 Hz) is prominent in the brain and it is transmitted partly linearly to the spinal cord and muscles. Multiple views on the functional relevance of beta activity in the motor system have been proposed. Previous simulation work suggested that pools of spinal motoneurons (MNs) receiving a common beta input could demodulate this activity, transforming it into low-frequency neural drive that could alter force production in muscles. This may suggest that common beta inputs to muscles have a direct role in force modulation. Here we report the experimental average levels and ranges of common beta activity in spinal MNs projecting to single muscles and use a computational model of a MN pool to test if the experimentally observed beta levels in MNs can influence force. When beta was modelled as a continuous activity, the amplitude needed to produce non-negligible changes in force corresponded to beta representation in the MN pool that was far above the experimental observations. On the other hand, when beta activity was modelled as short-lived events (i.e. bursts of beta activity separated by intervals without beta oscillations), this activity approximated levels that could cause small changes in force with estimated average common beta inputs to the MNs compatible with the experimental observations. Nonetheless, bursting beta is unlikely to be used for force control due to the temporal sparsity of this activity. It is therefore concluded that beta oscillations are unlikely to contribute to the voluntary modulation of force.
000120152 536__ $$9info:eu-repo/grantAgreement/EC/H2020/899626/EU/NIMA: Non-invasive Interface for Movement Augmentation/NIMA$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 899626-NIMA
000120152 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000120152 590__ $$a5.5$$b2022
000120152 592__ $$a1.557$$b2022
000120152 591__ $$aPHYSIOLOGY$$b10 / 79 = 0.127$$c2022$$dQ1$$eT1
000120152 593__ $$aSports Science$$c2022$$dQ1
000120152 591__ $$aNEUROSCIENCES$$b59 / 272 = 0.217$$c2022$$dQ1$$eT1
000120152 593__ $$aPhysiology$$c2022$$dQ1
000120152 594__ $$a9.9$$b2022
000120152 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000120152 700__ $$0(orcid)0000-0001-8439-151X$$aIbáñez, Jaime
000120152 700__ $$aFarina, Dario
000120152 773__ $$g601, 15 (2022), 3173-3185$$pJ. physiol.$$tJOURNAL OF PHYSIOLOGY-LONDON$$x0022-3751
000120152 8564_ $$s1914198$$uhttps://zaguan.unizar.es/record/120152/files/texto_completo.pdf$$yVersión publicada
000120152 8564_ $$s2124722$$uhttps://zaguan.unizar.es/record/120152/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000120152 909CO $$ooai:zaguan.unizar.es:120152$$particulos$$pdriver
000120152 951__ $$a2024-03-18-14:21:29
000120152 980__ $$aARTICLE