120152 20240319081003.0 doi 10.1113/JP283398 sideral 131031 ART-2022-131031 eng Zicher, Blanka Beta inputs to motor neurons do not directly contribute to volitional force modulation 2022 Access copy available to the general public Unrestricted Neural oscillatory activity in the beta band (13–30 Hz) is prominent in the brain and it is transmitted partly linearly to the spinal cord and muscles. Multiple views on the functional relevance of beta activity in the motor system have been proposed. Previous simulation work suggested that pools of spinal motoneurons (MNs) receiving a common beta input could demodulate this activity, transforming it into low-frequency neural drive that could alter force production in muscles. This may suggest that common beta inputs to muscles have a direct role in force modulation. Here we report the experimental average levels and ranges of common beta activity in spinal MNs projecting to single muscles and use a computational model of a MN pool to test if the experimentally observed beta levels in MNs can influence force. When beta was modelled as a continuous activity, the amplitude needed to produce non-negligible changes in force corresponded to beta representation in the MN pool that was far above the experimental observations. On the other hand, when beta activity was modelled as short-lived events (i.e. bursts of beta activity separated by intervals without beta oscillations), this activity approximated levels that could cause small changes in force with estimated average common beta inputs to the MNs compatible with the experimental observations. Nonetheless, bursting beta is unlikely to be used for force control due to the temporal sparsity of this activity. It is therefore concluded that beta oscillations are unlikely to contribute to the voluntary modulation of force. info:eu-repo/grantAgreement/EC/H2020/899626/EU/NIMA: Non-invasive Interface for Movement Augmentation/NIMA This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 899626-NIMA info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 5.5 2022 PHYSIOLOGY 10 / 79 = 0.127 2022 Q1 T1 NEUROSCIENCES 59 / 272 = 0.217 2022 Q1 T1 1.557 2022 Sports Science 2022 Q1 Physiology 2022 Q1 9.9 2022 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Ibáñez, Jaime (orcid)0000-0001-8439-151X Farina, Dario 601, 15 (2022), 3173-3185 J. physiol. JOURNAL OF PHYSIOLOGY-LONDON 0022-3751 1914198 http://zaguan.unizar.es/record/120152/files/texto_completo.pdf Versión publicada 2124722 http://zaguan.unizar.es/record/120152/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:120152 articulos driver 2024-03-18-14:21:29 ARTICLE